An IgD extramedullary plasmacytoma involving the sphenoid sinus at onset: an immunohistochemical study.
Laryngoscope
; 93(11 Pt 1): 1476-80, 1983 Nov.
Article
en En
| MEDLINE
| ID: mdl-6355718
A 60-year-old man developed a left VIth-nerve paralysis and underwent biopsy of an extramedullary plasmacytoma in the sphenoid sinus. Immunohistochemistry demonstrated cytoplasmic IgD and lambda determinants. Subsequent specimens from left clavical and thoracic epidural lesions also showed a plasma cell neoplasm with IgD and lambda determinants. No abnormal plasma cells were found in bone marrow specimens. Lambda Bence-Jones protein and monoclonal IgD-lambda protein in the serum were detected several months after onset. The patient died with disseminated plasmacytoma 1 year after diagnosis. The mode of presentation, pattern of metastasis, and secretory features were typical of extramedullary plasmacytoma arising in the upper airway. Immunohistochemistry was more productive than serum electrophoresis and immunoelectrophoresis for following the course of this neoplasm.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plasmacitoma
/
Seno Esfenoidal
/
Inmunoglobulina D
/
Neoplasias de los Senos Paranasales
/
Mieloma Múltiple
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Laryngoscope
Asunto de la revista:
OTORRINOLARINGOLOGIA
Año:
1983
Tipo del documento:
Article
Pais de publicación:
Estados Unidos