The Genain Quadruplets: electrophysiological, positron emission, and X-ray tomographic studies.

Buchsbaum, M S; Mirsky, A F; DeLisi, L E; Morihisa, J; Karson, C N; Mendelson, W B; King, A C; Johnson, J; Kessler, R

Buchsbaum, M S; Mirsky, A F; DeLisi, L E; Morihisa, J; Karson, C N; Mendelson, W B; King, A C; Johnson, J; Kessler, R.

Psychiatry Res ; 13(1): 95-108, 1984 Sep.

Article en En | MEDLINE | ID: mdl-6334864

RESUMEN

Four 51-year-old monozygotic quadruplets concordant for schizophrenia, originally studied at the National Institute of Mental Health 25 years ago, were restudied with topographic electroencephalography (EEG), evoked potentials (EPs), computed tomography (CT scans), polysomnographic sleep recordings, and positron emission tomography (PET) with 18F-2-deoxyglucose. EEG and EP findings were consistent with those from other groups of patients with schizophrenia and showed great similarity within the quadruplets. CT scans revealed uniformly small lateral ventricles. PET scans replicated earlier findings of relatively low glucose use in the frontal lobes but did not show strong familial concordance.

Asunto(s)

Encéfalo/fisiopatología; Cuádruples; Esquizofrenia/genética; Encéfalo/diagnóstico por imagen; Electroencefalografía; Potenciales Evocados Auditivos; Potenciales Evocados Visuales; Femenino; Lóbulo Frontal/metabolismo; Glucosa/metabolismo; Humanos; Persona de Mediana Edad; Embarazo; Cuádruples/psicología; Esquizofrenia/fisiopatología; Sueño/fisiología; Tomografía Computarizada de Emisión; Tomografía Computarizada por Rayos X

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cuádruples / Esquizofrenia / Encéfalo Límite: Female / Humans / Middle aged / Pregnancy Idioma: En Revista: Psychiatry Res Año: 1984 Tipo del documento: Article Pais de publicación: Irlanda

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