Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor.
Nature
; 305(5935): 605-8, 1983.
Article
en En
| MEDLINE
| ID: mdl-6312326
The predicted amino acid sequence of the simian sarcoma virus (SSV) transforming gene product, p28sis, closely corresponds to that of human platelet-derived growth factor (PDGF). We demonstrate that p28sis rapidly undergoes a series of discrete processing steps including dimer formation and proteolytic digestion to yield molecules structurally and immunologically resembling biologically active PDGF.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Retroviridae
/
Proteínas Virales
/
Factor de Crecimiento Derivado de Plaquetas
/
Virus del Sarcoma del Mono Lanudo
/
Genes Virales
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Nature
Año:
1983
Tipo del documento:
Article
Pais de publicación:
Reino Unido