alpha- and beta-adrenergic binding sites in sheep cerebral cortex: characterisation, effects of photoperiod and treatment with estrogen/progesterone.
Brain Res Bull
; 10(1): 159-61, 1983 Jan.
Article
en En
| MEDLINE
| ID: mdl-6297689
The radioligands [3H]-dihydroergocryptine and [3H]-dihydroalprenolol were used to characterise alpha- and beta-adrenergic binding sites, respectively, in membrane fractions of sheep cerebral cortex. In terms of affinity, density and specificity these sites possess properties similar to those previously characterised in rat brain. Further, in preliminary studies, these sites also appear to be responsive to treatment with estradiol/progesterone as well as to photoperiod. Thus, estrogen treatment can elevate both alpha- and beta-adrenergic binding sites in cortical tissue of sheep kept in natural light. In contrast, artificial light either has no effect or inhibits binding in response to estrogen.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Progesterona
/
Corteza Cerebral
/
Receptores Adrenérgicos
/
Receptores Adrenérgicos alfa
/
Receptores Adrenérgicos beta
/
Estradiol
/
Luz
Límite:
Animals
Idioma:
En
Revista:
Brain Res Bull
Año:
1983
Tipo del documento:
Article
Pais de publicación:
Estados Unidos