Temporary spinalization reverses the inhibitory effect of cyclazocine on the nociceptive response of rabbit spinal dorsal horn lamina V-type neurons.
Eur J Pharmacol
; 78(2): 237-40, 1982 Feb 26.
Article
en En
| MEDLINE
| ID: mdl-6281034
Cyclazocine (0.5 mg/kg i.v.) inhibited the activity of lamina V-type neurons of the rabbit spinal dorsal horn induced by intra-arterial injection of bradykinin. This inhibition was reversed during temporary spinalization by cold block. Thus, cyclazocine probably depresses nociceptive transmission in the spinal dorsal horn by facilitating descending inhibitory systems which originate from supraspinal structures.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dolor
/
Médula Espinal
/
Ciclazocina
/
Neuronas
Límite:
Animals
Idioma:
En
Revista:
Eur J Pharmacol
Año:
1982
Tipo del documento:
Article
Pais de publicación:
Países Bajos