Some aspects of macrophage behavior at the implant interface.
J Biomed Mater Res
; 18(4): 395-401, 1984 Apr.
Article
en En
| MEDLINE
| ID: mdl-6234318
The macrophage plays a pivotal role in both wound healing and cellular response to implants, including percutaneous devices. Within twenty-four hours macrophages were found in close contact with the implant surface. Eventually fibroplasts and connective tissue proliferate, and finally the implant will be encapsulated. The presence of macrophages is essential for the activation of collagen synthesis by fibroplasts . Implant shape and surface can profoundly affect macrophage behavior. At rough implant surfaces macrophages with giant cells are present for many months with the possibility of chronic granulomatous reactions. Superior tissue compatibility should be associated with smooth, well contoured implants with no acute angles.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Prótesis e Implantes
/
Cicatrización de Heridas
/
Macrófagos
/
Músculos
Límite:
Animals
Idioma:
En
Revista:
J Biomed Mater Res
Año:
1984
Tipo del documento:
Article
Pais de publicación:
Estados Unidos