[Behavior of complement factors and plasma proteins in burns]. / Comportamento di alcuni fattori del complemento e di alcune proteine plasmatiche nella malattia da ustione.
Arch Sci Med (Torino)
; 138(1): 63-92, 1981.
Article
en It
| MEDLINE
| ID: mdl-6166276
The behaviour of three complement components (C3, C4 and C3 activator), alpha 1, alpha 2, IgA, IgG, IgM, total proteins, and gamma globulins was followed 114 patients at the C.T.O. Turin, Burns Centre with burns covering from 15% to over 70% of the body surface. Forty-two died within a relatively short time. In the remaining 72, the parameters were studied almost daily for over 30 days, or even until a final cure was obtained. The complement data and, more particularly, the distinct increased in alpha-globulins made it clear that burns can be acute inflammations. In addition, initial immune depression is followed by a prompt response of the complement system (responsible for aspecific immunity). That this change is vital in the progress of the disease may be deduced from the fact that complement component levels were constantly below normal in the patients who died.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quemaduras
/
Complemento C3
/
Complemento C4
/
Enzimas Activadoras de Complemento
/
Proteínas Sanguíneas
/
Convertasas de Complemento C3-C5
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
It
Revista:
Arch Sci Med (Torino)
Año:
1981
Tipo del documento:
Article
Pais de publicación:
Italia