Human chorionic gonadotropin in intrauterine device users.
Int J Fertil
; 25(2): 134-6, 1980.
Article
en En
| MEDLINE
| ID: mdl-6117529
ABSTRACT
PIP: It has been reported that HCG (human chorionic gonadotropins) found in IUD users is a sign of an implantation of fertilized ovum, and that irregular bleeding in the IUD users may be a sign of an early abortion. Other authors contend, however, that HCG levels found in IUD wearers coincide with the peak of LH (luteinizing hormone) and are therefore a sign of cross reaction rather than the actual presence of real HCG. This study was conducted to investigate the presence of HCG during the luteal phase of 21 IUD wearers (aged 22 to 39 years) with menstrual cycles ranging from 25 to 33 days. A total of 80 blood samples was collected and analyzed for levels of HCG B-subunit, LH, and progesterone using radioimmunoassays. 10 women did not exhibit measurable amounts of B-subunit of HCG. In the other 11, very small amounts of HCG were detected (all under 3 mIU/ml. In 1 case, level of progesterone measured (0.6 to 0.7 ng/ml) pointed to a lack of ovulation while in another case, the highest level of HCG (2.5 mIU/ml paralleled the peak of LH reached at 44.6 mIU/ml. The findings suggest that cross reactivity causes the presence of small amounts of HCG in the blood of IUD wearers.
Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Gonadotropina Coriónica
/
Dispositivos Intrauterinos
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Int J Fertil
Año:
1980
Tipo del documento:
Article
Pais de publicación:
Estados Unidos