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The effect of menopausal status and sequential mestranol and norethisterone on serum cholesterol, triglyceride and electrophoretic lipoprotein patterns.
Br J Obstet Gynaecol ; 86(10): 810-5, 1979 Oct.
Article en En | MEDLINE | ID: mdl-508663
ABSTRACT
PIP: Incidence of cardiovascular disease increases in postmenopausal women and may be related to elevated serum lipid concentrations. The serum cholestrol, triglycerides, and electrophoretic lipoprotein patterns of 35 postmenopausal women receiving sequential mestranol and norethisterone showed a reduction of serum cholesterol with concurrent increase in serum triglycerides after 2 months therapy. Postmenopausal women who were not treated had greater serum cholesterol concentration than either the treated postmenopausal women or 35 premenopausal women matched for age and weight. However, there were no significant concentration differences between the treated postmenopausal women and premenopausal women. It is uncertain whether reduced serum cholesterol levels will reduce the incidence of coronary artery disease nor whether administering estrogens and progestogens will reduce coronary artery disease since there is a marked alteration in lipid metabolism at menopause.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Menopausia / Colesterol / Lipoproteínas / Mestranol / Noretindrona Límite: Adult / Female / Humans / Middle aged Idioma: En Revista: Br J Obstet Gynaecol Año: 1979 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Menopausia / Colesterol / Lipoproteínas / Mestranol / Noretindrona Límite: Adult / Female / Humans / Middle aged Idioma: En Revista: Br J Obstet Gynaecol Año: 1979 Tipo del documento: Article Pais de publicación: Reino Unido