Chlorambucil therapy in childhood nephrotic syndrome.
S Afr Med J
; 55(24): 971-5, 1979 Jun 09.
Article
en En
| MEDLINE
| ID: mdl-472947
Chlorambucil (Leukeran), a cytotoxic agent, was administered to 13 children with the nephrotic syndrome who had responded to steroid therapy, but frequently relapsed. In all patients corticosteroid therapy had become unsatisfactory. Eleven patients have so far remained in remission for an average follow-up period of 31 months since chlorambucil therapy. No side-effects of therapy were observed in this study, but several grave complications of high-dosage therapy have been reported in the recent literature. A dose of 0.2 mg/kg/d for 8 weeks should not be exceeded.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Clorambucilo
/
Síndrome Nefrótico
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
S Afr Med J
Año:
1979
Tipo del documento:
Article
Pais de publicación:
Sudáfrica