Studies on the activity of phorbol myrystate acetate on the human polymorphonuclear leukocytes.
Experientia
; 35(6): 830-1, 1979 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-467608
Phorbol myrystate acetate (PMA) activates nitroblue tetrazolium reduction in human polymorphs. The activation is inhibited by dibutyryl cyclic AMP, theophylline and phenylbutazone, but is not influenced by hydrocortisone in vitro, nor is it inhibited by leukocytes from patients treated with prednisone. Peptide analogues of Tuftsin also had no effect on this stimulatory activity. We conclude that the action of PMA on the nitroblue tetrazolium reduction is mediated through cyclic nucleotides.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Forboles
/
Acetato de Tetradecanoilforbol
/
Neutrófilos
Límite:
Adult
/
Humans
Idioma:
En
Revista:
Experientia
Año:
1979
Tipo del documento:
Article
Pais de publicación:
Suiza