Specificity in the factor VIII response to vasopressin infusion in man.
Br J Haematol
; 41(3): 437-47, 1979 Mar.
Article
en En
| MEDLINE
| ID: mdl-427046
Structural requirements of the systemic factor VIII response to intravenous vasopressin in man has been investigated using vasopressin analogues. With the analogues available the receptor specificity of this phenomenon could not be distinguished from those associated with the previously described plasminogen activator release or antidiuretic effects of this hormone. Further studies using 1-desamino-[8-D-arginine]vasopressin showed a dose-related release of both procoagulant and antigenic components of the factor VIII complex. The newly released factor VIII could not be distinguished from circulating factor VIII on the basis of molecular size, electrophoretic mobility or in vitro stability despite apparent differences in the duration of response of the procoagulant and antigenic components in vivo.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Factor VIII
/
Vasopresinas
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Br J Haematol
Año:
1979
Tipo del documento:
Article
Pais de publicación:
Reino Unido