Hypnotic efficacy of lorazepam and flurazepam.
Clin Pharmacol Ther
; 19(2): 191-5, 1976 Feb.
Article
en En
| MEDLINE
| ID: mdl-4255
In a double-blind crossover study involving 15 insomniac subjects, the hypnotic efficacy of lorazepam, 2 and 4 mg, was compared with flurazepam, 15 and 30 mg, and placebo. Five subjective measures were used: onset, length, and depth of sleep, number of times awakened, and satisfaction with the hypnotic. Lorazepam in 2- and 4-mg doses was comparable in hypnotic efficacy to flurazepam, 30 mg, according to most parameters of measurement. Side effects were minor, although relatively numerous at the 4-mg doses.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ansiolíticos
/
Flurazepam
/
Trastornos del Inicio y del Mantenimiento del Sueño
/
Lorazepam
Tipo de estudio:
Clinical_trials
Límite:
Humans
/
Male
Idioma:
En
Revista:
Clin Pharmacol Ther
Año:
1976
Tipo del documento:
Article
Pais de publicación:
Estados Unidos