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Use of Optical Coherence Tomography to Assess Properties of Cutaneous Defects Following Radiofrequency Microneedling and Laser Treatment.
Seiger, Kira; Driscoll, William; Messele, Feben; Golbari, Nicole M; Fan, Xiying; Holmes, Jon; Zachary, Christopher B.
Afiliación
  • Seiger K; Department of Dermatology, University of California San Francisco, San Francisco, California, USA.
  • Driscoll W; Department of Dermatology, University of California Irvine, Irvine, California, USA.
  • Messele F; Department of Dermatology, University of California Irvine, Irvine, California, USA.
  • Golbari NM; Department of Dermatology, University of California Irvine, Irvine, California, USA.
  • Fan X; Department of Dermatology, University of California Irvine, Irvine, California, USA.
  • Holmes J; Michelson Diagnostics Ltd, Maidstone, England, UK.
  • Zachary CB; Department of Dermatology, University of California Irvine, Irvine, California, USA.
Lasers Surg Med ; 2024 Sep 22.
Article en En | MEDLINE | ID: mdl-39308122
ABSTRACT

OBJECTIVES:

To characterize the properties of cutaneous defects created by energy-based devices using optical coherence tomography. MATERIALS AND

METHODS:

Radiofrequency (RF) microneedling and non-ablative fractional laser (NAFL) treatment were performed in vivo with various parameters. Following treatment, optical coherence tomography (OCT) was used to image and measure cutaneous defects at multiple time points over a 24 h period.

RESULTS:

Channel-like cutaneous defects were visible with OCT following bipolar RF microneedling and NAFL treatment. Using a double pulse technique with RF microneedling yielded a greater number of defects visible with OCT, as well as defects that were deeper and more durable over time. Following treatment with 1927 nm thulium fiber laser, the average diameter of the defects was greater when the energy level was 20 mJ as compared to 10 mJ (0.33 mm vs. 0.27 mm, p < 0.01).

CONCLUSIONS:

Cutaneous defects were observed following both RF microneedling and NAFL treatment. Properties of the cutaneous defects varied based on device, treatment setting, and technique, which may be useful in guiding further study of device-assisted drug delivery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Lasers Surg Med Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Lasers Surg Med Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos