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Infection prevention and control risk factors for SARS-CoV-2 infection in health workers: a global, multicentre case-control study.
Cassini, Alessandro; Yin, Mo; Simniceanu, Alice; Gon, Giorgia; Cowling, Benjamin J; Allegranzi, Benedetta.
Afiliación
  • Cassini A; Infection Prevention and Control Hub and Task Force, Integrated Health Services, UHC/Life Course, World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland; Public Health Department, Canton of Vaud, 2 Avenues des Casernes, 1014 Lausanne, Switzerland; Infectious Diseases Service, Lausanne
  • Yin M; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, United Kingdom; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand; Div
  • Simniceanu A; Infection Prevention and Control Hub and Task Force, Integrated Health Services, UHC/Life Course, World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland; Emerging Diseases and Zoonoses Unit, Epidemic and Pandemic Preparedness and Prevention Department, World Health Organization, Avenue
  • Gon G; Department of Infectious Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom.
  • Cowling BJ; WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Allegranzi B; Infection Prevention and Control Hub and Task Force, Integrated Health Services, UHC/Life Course, World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland. Electronic address: allegranzib@who.int.
J Hosp Infect ; 2024 Sep 20.
Article en En | MEDLINE | ID: mdl-39307426
ABSTRACT

BACKGROUND:

Health workers were at higher risk for SARS-CoV-2 infection during the COVID-19 pandemic due to occupational risk factors. As part of the WHO Unity Studies initiative, we aimed to characterise these risk factors.

METHODS:

This global, multicentre, nested, case-control study was conducted in 121 healthcare facilities in 21 countries. Cases were health workers who tested positive for SARS-CoV-2 infection with a documented occupational exposure to COVID-19 patients in the 14 days pre-enrolment. Controls were enrolled from the same facility with a similar exposure but negative serology. Case and control status was confirmed with serological testing at baseline and after 3-4 weeks. Demographic and infection risk factor data were collected using structured questionnaires.

FINDINGS:

Between June 2020 and December 2021, data were obtained for 1213 cases and 1844 controls. SARS-CoV-2 infection risk was associated with non-adherence to personal protective equipment (PPE) guidelines (aOR 1·67 [95% CI 1·32-2·12]) and not consistently performing hand hygiene after patient contact (aOR 2·52 [1·72-3·68]). Direct close contact with COVID-19 patients was also associated with an increased risk, particularly during prolonged contact (>15 min.). Items associated with a lower risk were respirators during aerosol-generating procedures and gloves, gowns or coveralls during contact with contaminated materials/surfaces. No difference was observed among health workers using respirators versus surgical masks for routine care.

CONCLUSION:

Appropriate implementation of infection prevention and control measures and PPE use remain a priority to protect health workers from SARS-CoV-2 infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Hosp Infect Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Hosp Infect Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido