Herpes zoster ophthalmicus uveitis: onset and complications: Herpes Zoster Uveitis.
Am J Ophthalmol
; 2024 Sep 20.
Article
en En
| MEDLINE
| ID: mdl-39307262
ABSTRACT
PURPOSE:
To describe the timing of uveitis onset and frequency of associated complications in individuals with herpes zoster ophthalmicus (HZO).DESIGN:
Retrospective, cohort studyMETHODS:
Individuals with acute HZO seen at the Auckland District Health Board from 2006 to 2016 were studied. The primary outcome measures were the proportion who developed uveitis and time to diagnosis of uveitis following the onset of HZO. Secondary outcome measures included complications of HZO uveitis and effects of prompt antiviral (within 72 hours) on outcomes.RESULTS:
869 patients with HZO were included for analysis, of whom 413 (47.6%) developed uveitis. Median time from onset of rash to diagnosis of uveitis was 10 days (IQR 6 - 14). Of the 658 individuals examined within the first week following rash onset (days 0 through 7), 17.6% (116/658) were diagnosed with uveitis at that initial presenting examination, with an additional 24.9% (164/658) diagnosed with uveitis at a subsequent visit. Complications were higher in eyes with uveitis, including moderate or severe vision loss, corneal scarring, neurotrophic keratitis, band keratopathy, corneal melt, elevated intraocular pressure, glaucoma, and cataract (all p<0.01). Prompt antiviral was associated with a lower rate of moderate vision loss among eyes with uveitis (p=0.02).CONCLUSIONS:
Uveitis occurred in approximately half of individuals with HZO and was most frequently diagnosed during the second week following rash onset. Eyes with uveitis were more likely to have other ocular complications and loss of vision.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Am J Ophthalmol
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos