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CharActeristics, sizing anD outcomes of stenotic, tapered, rapHe-type bicuspid aOrtic valves treated with trans-catheter device implantation: Insights the AD HOC registry.
Buono, Andrea; De Biase, Chiara; Fabris, Tommaso; Bellamoli, Michele; Kim, Won-Keun; Montarello, Nicholas; Costa, Giuliano; Zito, Andrea; Alfadhel, Mesfer; Koren, Ofir; Fezzi, Simone; Bellini, Barbara; Massussi, Mauro; Scotti, Andrea; Bai, Lin; Costa, Giulia; Mazzapicchi, Alessandro; Giacomin, Enrico; Gorla, Riccardo; Latini, Alessia; Fraccaro, Chiara; Sondergaard, Lars; Strazzieri, Orazio; Boiago, Mauro; Busco, Marco; Charitos, Efstratios; Orbach, Ady; Messina, Antonio; Bettari, Luca; Navazio, Edoardo; Paglianiti, Donato Antonio; Nagasaka, Takashi; Napodano, Massimo; Villa, Emmanuel; Angelillis, Marco; Ielasi, Alfonso; Landes, Uri; Brambilla, Nedy; Bedogni, Francesco; Mangieri, Antonio; Saia, Francesco; Favero, Luca; Chen, Mao; Adamo, Marianna; Latib, Azeem; Petronio, Anna Sonia; Montorfano, Matteo; Makkar, Raj R; Mylotte, Darren; Blackman, Daniel J.
Afiliación
  • Buono A; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • De Biase C; Clinique Pasteur, Toulouse, France.
  • Fabris T; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Medical School, Padua, Italy.
  • Bellamoli M; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • Kim WK; Kerckhoff Heart Center, Bad Nauheim, Germany.
  • Montarello N; The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Costa G; U.O.C. Cardiologia, Centro Alte Specialità e Trapianti, P.O. G. Rodolico, A.O.U. Policlinico-V. Emanuele, Università di Catania, Catania, Italy.
  • Zito A; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
  • Alfadhel M; Department of Cardiology, Leeds Teaching Hospitals NHS Trust Leeds, UK.
  • Koren O; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America.
  • Fezzi S; Department of Cardiology, University Hospitals Galway, Ireland.
  • Bellini B; Cardio-Thoracic-Vascular Department, San Raffaele Scientific Institute, Milan, Italy.
  • Massussi M; Civil Hospital and University of Brescia, Brescia, Italy.
  • Scotti A; Montefiore Medical Center, New York, NY, USA.
  • Bai L; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
  • Costa G; Cardiac Catheterization Laboratory, University of Pisa and Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
  • Mazzapicchi A; Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
  • Giacomin E; Cardiology Unit, Cardio-Neuro-Vascular Department, Ca' Foncello Hospital Azienda N 2 Marca Trevigiana, Treviso, Italy.
  • Gorla R; Department of Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
  • Latini A; Cardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy.
  • Fraccaro C; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Medical School, Padua, Italy.
  • Sondergaard L; The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Abbott Structural Heart, Santa Clara, CA, USA.
  • Strazzieri O; U.O.C. Cardiologia, Centro Alte Specialità e Trapianti, P.O. G. Rodolico, A.O.U. Policlinico-V. Emanuele, Università di Catania, Catania, Italy.
  • Boiago M; Clinique Pasteur, Toulouse, France.
  • Busco M; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
  • Charitos E; Kerckhoff Heart Center, Bad Nauheim, Germany.
  • Orbach A; Edith Wolfson Medical Center, Cardiology Department, Holon, Israel and Tel-Aviv University, Tel-Aviv, Israel.
  • Messina A; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • Bettari L; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • Navazio E; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • Paglianiti DA; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
  • Nagasaka T; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America.
  • Napodano M; Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua Medical School, Padua, Italy.
  • Villa E; Valve Center, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • Angelillis M; Cardiac Catheterization Laboratory, University of Pisa and Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
  • Ielasi A; Division of Cardiology, IRCCS Hospital Galeazzi-Sant'Ambrogio, Milan, Italy.
  • Landes U; Edith Wolfson Medical Center, Cardiology Department, Holon, Israel and Tel-Aviv University, Tel-Aviv, Israel.
  • Brambilla N; Department of Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
  • Bedogni F; Department of Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
  • Mangieri A; Cardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy.
  • Saia F; Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
  • Favero L; Cardiology Unit, Cardio-Neuro-Vascular Department, Ca' Foncello Hospital Azienda N 2 Marca Trevigiana, Treviso, Italy.
  • Chen M; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
  • Adamo M; Civil Hospital and University of Brescia, Brescia, Italy.
  • Latib A; Montefiore Medical Center, New York, NY, USA.
  • Petronio AS; Cardiac Catheterization Laboratory, University of Pisa and Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
  • Montorfano M; Cardio-Thoracic-Vascular Department, San Raffaele Scientific Institute, Milan, Italy.
  • Makkar RR; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America.
  • Mylotte D; Department of Cardiology, University Hospitals Galway, Ireland.
  • Blackman DJ; Department of Cardiology, Leeds Teaching Hospitals NHS Trust Leeds, UK.
Int J Cardiol ; : 132569, 2024 Sep 18.
Article en En | MEDLINE | ID: mdl-39303924
ABSTRACT

BACKGROUND:

Raphe-type bicuspid aortic valve (BAV) is a potential hostile scenario in trans-catheter aortic valve replacement (TAVR) due to pronounced calcium burden, possibly associated with tapered valve configuration. Trans-Catheter heart valve (THV) sizing strategy (annular vs. supra-annular) is controversial in this valve subtype.

OBJECTIVES:

To describe the phenotypical characteristics of severe, tapered, raphe-type, BAV stenosis undergoing TAVR and to explore safety and efficacy of modern-generation THVs, analysing the impact of annular and supra-annular sizing strategies on short- and mid-terms outcomes.

METHODS:

This is a retrospective, multicenter registry enrolling consecutive stenotic Sievers type 1 BAV treated with TAVR. Study population was divided into tapered and non-tapered configuration according to MSCT analysis. Matched comparison between annular and supra-annular sizing groups was performed in tapered population.

RESULTS:

From January 2016 to June 2023, 897 patients were enrolled. Of them, 696 patients displayed a tapered configuration. Of those, 510 received a THV according to annular sizing. After propensity score matching 186 matched pairs were selected. Technical success (96.2 % vs 94.1 %, OR 1.61 [0.61-4.24], p = 0.34), 30-day device success (83.6 % in both groups, OR 1.42 [0.78-2.57], p = 0.25) and 30-day early safety (71.8 % vs 70.5 %, OR 1.07 [0.68-1.68], p = 0.78) were similar between the annular and supra-annular sizing groups; a higher post-TAVR gradient was observed in supra-annular group, although it was only 2 mmHg mean. At mid-term follow-up, the rate of clinical efficacy was 84.7 %.

CONCLUSIONS:

TAVR with modern-generation devices is safe and effective for tapered raphe-type BAV, showing comparable results for annular and supra-annular sizing strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos