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The characteristics of three-dimensional real inversion recovery MRI sequence in delayed Meniere's disease.
Liu, Xu; Guo, Linying; Shi, Suming; Wang, Wuqing.
Afiliación
  • Liu X; ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.
  • Guo L; Department of Otorhinolaryngology, NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China.
  • Shi S; Department of Radiology, Eye&ENT Hospital, Fudan University, Shanghai, China.
  • Wang W; ENT Institute and Otorhinolaryngology Department, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.
Acta Otolaryngol ; : 1-4, 2024 Sep 20.
Article en En | MEDLINE | ID: mdl-39301640
ABSTRACT

BACKGROUND:

Delayed Meniere's disease (DMD) is characterized by episodic vertigo occurring after a significant delay following longstanding sensorineural hearing loss. However, its pathogenesis and characteristics remain unclear.

OBJECTIVES:

To explore the characteristics of endolymphatic hydrops (EH) in DMD and investigate its pathology using MRI. MATERIALS AND

METHODS:

17 patients diagnosed with DMD were included in this study. A 3D-real-IR MRI sequence was utilized to visualize and grade EH. The signal intensity of the basal cochlear turn was compared to that of the cerebellar white matter to calculate the CC ratio. A paired t-test was employed to assess the differences in the CC ratio between the affected and unaffected sides in patients with unilateral DMD.

RESULTS:

EH was present in 100% of cases on the affected side. Unilateral EH was seen in 82.4%, and bilateral EH in 23.5%. Vestibular EH without cochlear involvement occurred in 29.4%, and cochlear EH without vestibular involvement in 5.9%. The CC ratio was significantly higher on the affected side (p < 0.01). CONCLUSIONS AND

SIGNIFICANCE:

A significant grade of vestibular EH was observed in DMD, with bilateral EH being relatively common. The increased contrast on the affected side may reflect the underlying pathology in DMD patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Otolaryngol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Otolaryngol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido