In situ hybridization and translocation breakpoint mapping. II. Two unusual t(21;22) translocations.
Cytogenet Cell Genet
; 39(3): 173-8, 1985.
Article
en En
| MEDLINE
| ID: mdl-3930156
Using a combination of banding techniques, we examined two atypical 21;22 translocations, 46,XX or XY,t(21;22)(p11;q11). In situ chromosomal hybridization of a probe for the constant region of the lambda light chain locus demonstrated that the 22q11 breakpoints of both rearrangements were proximal to the C lambda gene cluster. These studies permitted us to distinguish the 22q11 breakpoints of these translocations from the breakpoint of the 22q--chromosome of chronic myelogenous leukemia.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Translocación Genética
/
Cromosomas Humanos 21-22 e Y
/
Cadenas lambda de Inmunoglobulina
/
Cadenas Ligeras de Inmunoglobulina
Límite:
Female
/
Humans
Idioma:
En
Revista:
Cytogenet Cell Genet
Año:
1985
Tipo del documento:
Article
Pais de publicación:
Suiza