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Finite element analysis and in vitro tests on endurance life and durability of composite bone substitutes.
Seraji, Amir Abbas; Nahavandi, Reza; Kia, Amir; Rabbani Doost, Ahad; Keshavarz, Vahid; Sharifianjazi, Fariborz; Tavamaishvili, Ketevan; Makarem, Dorna.
Afiliación
  • Seraji AA; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada.
  • Nahavandi R; Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran.
  • Kia A; Department of Biochemical and Pharmaceutical Engineering, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
  • Rabbani Doost A; Department of Mechanical Engineering, University of Guilan, Rasht, Iran.
  • Keshavarz V; Department of Biomaterials, Iran Polymer and Petrochemical Institute, Tehran, Iran.
  • Sharifianjazi F; Department of Materials Engineering, Faculty of Engineering and Technology, Imam Khomeini International University, Qazvin, Iran.
  • Tavamaishvili K; Center for Advanced Materials and Structures, School of Science and Technology, The University of Georgia, Tbilisi, Georgia.
  • Makarem D; School of Medicine, Georgian American University, Tbilisi, Georgia.
Front Bioeng Biotechnol ; 12: 1417440, 2024.
Article en En | MEDLINE | ID: mdl-39301173
ABSTRACT
Bone structures facilitate the regeneration and repair of bone tissue in regions where it has been damaged or destroyed, either temporarily or permanently. Therefore, the bone's fatigue strength and durability are crucial to its efficacy and longevity. Several variables, such as the construct's material qualities, design, and production procedure, loading and unloading cycles, and physiological conditions influence the endurance life of bone constructs. Metals, ceramics, and polymers are all routinely utilized to create bone substitutes, and each of these materials has unique features that might affect the fatigue strength and endurance life of the final product. The mechanical performance and capacity to promote bone tissue regeneration may be affected by the scaffold's design, porosity, and pore size. Researchers employ mechanical testing under cyclic loading circumstances as one example of an experimental approach used to assess bone construction endurance. These analyses can give us important information about the stress-strain behavior, resistance to multiple loading cycles, and fatigue strength of the new structure. Predicting the endurance life of the developed construct may also be possible with the use of simulations and numerical analyses. Hence, in order to create reliable and efficient constructs for bone tissue engineering, it is crucial to understand their fatigue strength and durability. The purpose of this study is to analyze the effective parameters for fatigue strength of bone structures and to gather the models and evaluations utilized in endurance life assessments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza