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Cyclodextrin-Based Nanogels for Stabilization and Sensing of Curcumin.
Casulli, Maria Antonietta; Yan, Ruyu; Takeuchi, Satomi; Cesari, Andrea; Mancin, Fabrizio; Hayashita, Takashi; Hashimoto, Takeshi; Taurino, Irene.
Afiliación
  • Casulli MA; Micro and Nano-Systems (MNS), Department of Electrical Engineering (ESAT), Katholieke Universiteit Leuven (KU Leuven), 3001 Leuven, Belgium.
  • Yan R; Graduate School of Science and Technology, Department of Materals and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan.
  • Takeuchi S; Graduate School of Science and Technology, Department of Materals and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan.
  • Cesari A; Department of Chemistry and Industrial Chemistry, University of Pisa, via G. Moruzzi 13, 56124 Pisa, Italy.
  • Mancin F; Department of Chemical Sciences, University of Padova, via Marzolo 1, 35131 Padova, Italy.
  • Hayashita T; Department of Chemical Sciences, University of Padova, via Marzolo 1, 35131 Padova, Italy.
  • Hashimoto T; Graduate School of Science and Technology, Department of Materals and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan.
  • Taurino I; Graduate School of Science and Technology, Department of Materals and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan.
ACS Appl Nano Mater ; 7(17): 20153-20162, 2024 Sep 13.
Article en En | MEDLINE | ID: mdl-39296865
ABSTRACT
Curcumin (CUR), a polyphenolic substance from turmeric, displays diverse medicinal properties. However, its instability poses challenges in detection. Cyclodextrin-based nanogels (CyDngs) offer a transformative solution, enhancing CUR's stability in aqueous solutions. Multisensing approaches involving fluorescence, electrochemistry, and NMR spectroscopy were employed, demonstrating CyDngs' pivotal role in CUR detection. Langmuir analysis revealed a binding constant of 1.4 × 104 M-1 for CyDngs, highlighting their effectiveness over native ß-CyDs. The study emphasized CyDngs' superiority in stabilizing CUR and enabling reliable and sensitive detection with very diverse methods.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Appl Nano Mater Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Appl Nano Mater Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos