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Retinal electrophysiological alterations are associated with cognition in early course psychosis.
Molho, Willa; Stiltner, Brendan; Raymond, Nicolas; Kiely, Chelsea; Trotti, Rebekah; Harris, Caroline; Bannai, Deepthi; Keshavan, Matcheri; Silverstein, Steven; Lizano, Paulo.
Afiliación
  • Molho W; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Stiltner B; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Raymond N; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Kiely C; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Trotti R; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Harris C; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Bannai D; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Keshavan M; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
  • Silverstein S; Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA.
  • Lizano P; Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Division of Translational Neuroscience, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address: plizano@bidmc.harvard.edu.
Schizophr Res ; 274: 137-141, 2024 Sep 17.
Article en En | MEDLINE | ID: mdl-39293251
ABSTRACT
Retinal electrophysiological alterations are implicated in psychosis, but their relationship with cognition in early course psychosis (ECP) is understudied. The Brief Assessment of Cognition (BAC) and flash electroretinography (fERG) were conducted in 24 controls (HC) and 27 ECP individuals. Partial Spearman correlations were performed between fERG and BAC. Lower Photopic-1b and Scotopic-3b amplitudes were identified in ECP vs. HCs. Correlations were significant (p<0.05) between BAC Composite score and a-wave S3a and S2a and b-wave S2b and S3b conditions. Thus, ECP was characterized by lower ERG responses, and lower rod/cone/bipolar cell responses were related to poorer cognition.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Schizophr Res Asunto de la revista: PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Schizophr Res Asunto de la revista: PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos