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Intravascular lymphoma: A diagnostic challenge for a treatable cause of rapidly progressive dementia.
Gonçalves, Trajano Aguiar Pires; Toniolo, Juliana Naback; Hemerly, Matheus Compart; Zotin, Maria Clara Zanon; de Moraes Alves, Anna Letícia; Messias, Katharina Vieira; Marques, Vanessa Daccach.
Afiliación
  • Gonçalves TAP; Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
  • Toniolo JN; Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
  • Hemerly MC; Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
  • Zotin MCZ; Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
  • de Moraes Alves AL; Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
  • Messias KV; Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
  • Marques VD; Department of Neurosciences and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil. Electronic address: vdaccachm@gmail.com.
J Neuroimmunol ; 396: 578459, 2024 Sep 11.
Article en En | MEDLINE | ID: mdl-39293227
ABSTRACT
Intravascular large B-cell lymphoma (IVLBCL) is a rare hematological malignancy where its development in the intravascular environment is the main characteristic. Despite its ability to affect multiple organic systems, there is a tropism for the central nervous system, which may be related to several clinical syndromes, making this condition a great mimic and consequently a diagnostic challenge. Rapidly progressive dementia may be one of the presenting phenotypes of IVLBCL. This case report aims to highlight the main red flags, such as sustained elevation of lactate dehydrogenase, organomegaly and specific lesions with vasculitis-like bleeding, all that can be used as clinical clues to direct the differential diagnosis. In addition, it reinforces the role of early brain biopsy in this context, since IVLBCL is a treatable disease.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Neuroimmunol Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Neuroimmunol Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos