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Association Between Systolic Blood Pressure and in-Hospital Mortality Among Congestive Heart Failure Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit: A Retrospective Cohort Study.
Zhang, Kai; Han, Yu; Gao, Yu Xuan; Gu, Fang Ming; Gu, Zhao Xuan; Liang, Jia Ying; Zhao, Jia Yu; Zhang, Tianqi; Gao, Min; Cai, Tian Yi; Hu, Rui; Liu, Tian Zhou; Li, Bo; Zhang, Yixin.
Afiliación
  • Zhang K; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Han Y; Department of Ophthalmology, First Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Gao YX; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Gu FM; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Gu ZX; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Liang JY; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Zhao JY; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Zhang T; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Gao M; Department of Cancer Center, First Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Cai TY; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Hu R; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Liu TZ; Department of Gastrointestinal Surgery, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Li B; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
  • Zhang Y; Cardiovascular Surgery Department, Second Hospital of Jilin University, Changchun, Jilin Province, People's Republic of China.
Int J Chron Obstruct Pulmon Dis ; 19: 2023-2034, 2024.
Article en En | MEDLINE | ID: mdl-39291240
ABSTRACT

Background:

There has been a growing body of research focusing on patients with Congestive Heart Failure (CHF) and chronic obstructive pulmonary disease (COPD) admitted to the intensive care unit (ICU). However, the optimal blood pressure (BP) level for such patients remains insufficiently explored. This study aimed to investigate the associations between systolic blood pressure (SBP) and in-hospital mortality among ICU patients with both CHF and COPD.

Methods:

This retrospective cohort study enrolled 6309 patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. SBP was examined as both a continuous and categorical variable, with the primary outcome being in-hospital mortality. The investigation involved multivariable logistic regression, restricted cubic spline regression, and subgroup analysis to determine the relationship between SBP and mortality.

Results:

The cohort consisted of 6309 patients with concurrent CHF and COPD (3246 females and 3063 males), with an average age of 73.0 ± 12.5 years. The multivariate analysis revealed an inverse association between SBP and in-hospital mortality, both as a continuous variable (odds ratio = 0.99 [95% CI, 0.99~1]) and as a categorical variable (divided into quintiles). Restricted cubic spline analysis demonstrated an L-shaped relationship between SBP and mortality risk (P nonlinearity < 0.001), with an inflection point at 99.479 mmHg. Stratified analyses further supported the robustness of this correlation.

Conclusion:

The relationship between SBP and in-hospital mortality in patients with both CHF and COPD follows an L-shaped pattern, with an inflection point at approximately 99.479 mmHg.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Sanguínea / Mortalidad Hospitalaria / Enfermedad Pulmonar Obstructiva Crónica / Insuficiencia Cardíaca / Unidades de Cuidados Intensivos Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Chron Obstruct Pulmon Dis Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Sanguínea / Mortalidad Hospitalaria / Enfermedad Pulmonar Obstructiva Crónica / Insuficiencia Cardíaca / Unidades de Cuidados Intensivos Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Chron Obstruct Pulmon Dis Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda