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Risk factors and severity of melasma in patients attending dermatology outpatient department of a tertiary care hospital: A cross-sectional study.
Shakya, Sunil; Pathak, Bishnu Deep; Lamichhane, Ramesh; Ghimire, Bhuwan; Devkota, Sameeksha; Ghimire, Sandesh; Shrestha, Prosess; Acharya, Sajana; Baniya, Sunil; Bogati, Kanchan; Pathak, Indra Dev; Dhakal, Bishal.
Afiliación
  • Shakya S; Department of Dermatology, Shree Birendra Hospital, Kathmandu, Nepal.
  • Pathak BD; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Lamichhane R; Department of Internal Medicine, Jalalabad Ragib Rabeya Medical College, Sylhet, Bangladesh.
  • Ghimire B; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Devkota S; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Ghimire S; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Shrestha P; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Acharya S; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Baniya S; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Bogati K; Department of Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Lalitpur, Nepal.
  • Pathak ID; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
  • Dhakal B; Department of Dermatology, Nepalese Army Institute of Health Sciences, College of Medicine, Kathmandu, Nepal.
Medicine (Baltimore) ; 103(37): e39674, 2024 Sep 13.
Article en En | MEDLINE | ID: mdl-39287320
ABSTRACT
Melasma is a chronic acquired dysfunction of melanogenesis characterized by dark brown irregular macules on skin. Genetic predisposition, pregnancy, sun exposure, and hormonal therapy are common risk factors. Prevalence of melasma is variable, ranging from 5% to 46%. This study aimed to assess the severity and potential risk factors of melasma in a tertiary care setting. An analytical cross-sectional study was conducted on patients with melasma visiting dermatology department of a tertiary care center in Nepal. Nonprobability consecutive sampling was adopted. Severity of melasma was assessed using the Modified Melasma Area and Severity Index score. Data analysis was performed using the Statistical Package for the Social Sciences, version-23. Bivariate analysis was done by using Student t test/Mann-Whitney U test, or Chi-square/Fischer exact test for continuous and categorical variables, respectively. The overall median Modified Melasma Area and Severity Index score was 5.40 (3.60-6.75). Most patients (168, 88.42%) had mild melasma. The severity score was significantly higher in older age (P = .024), women having parity more than 3 (P = .014), centrofacial pattern (P = .024), and patients having dermatological comorbidities (P = .014). Severity was significantly lower in those who used cosmetics at home. Moreover, the use of digital screens was not associated with an increase in melasma severity. Most of the cases had mild melasma. Severity was significantly associated with age, parity, pattern, practice of cosmetic use, and presence of dermatological comorbidities.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Centros de Atención Terciaria / Melanosis Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article País de afiliación: Nepal Pais de publicación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Centros de Atención Terciaria / Melanosis Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article País de afiliación: Nepal Pais de publicación: Estados Unidos