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Associations of minerals intake with colorectal cancer risk in the prostate, lung, colorectal, ovarian cancer screening trial.
Li, Siyue; Ren, Qingqian; Song, Zixuan; Liu, Baixue; Wang, Dan; Shang, Yanna; Wang, Hao.
Afiliación
  • Li S; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Ren Q; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Song Z; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Liu B; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Wang D; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Shang Y; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
  • Wang H; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
Front Nutr ; 11: 1445369, 2024.
Article en En | MEDLINE | ID: mdl-39285869
ABSTRACT

Objective:

Exploring the association between common mineral intake and the risk of colorectal cancer (CRC).

Methods:

We utilized the multivariate Cox proportional hazards model to assess the association between intake of minerals and the risk of CRC, estimating hazard ratios (HRs) and 95% confidence intervals (CIs).

Results:

A total of 101,686 eligible participants were included in the analysis of this study, including 1,100 CRC cases. After adjusting for potential confounders, we found that total zinc intake (HRQ4vs.Q1 0.79, 95%CI 0.67-0.93; P for trend <0.05), iron intake (HRQ4vs.Q1 0.81, 95%CI 0.68-0.96; P for trend <0.05), copper intake (HRQ4vs.Q1 0.80, 95%CI 0.68-0.95; P for trend <0.05), selenium intake (HRQ4vs.Q1 0.83, 95%CI 0.69-0.98; P for trend <0.05) were significantly negatively associated with the incidence of CRC, but magnesium intake in the appropriate range is associated with a reduced risk of CRC (HRQ3vs.Q1 0.77, 95%CI 0.65-0.91; P for trend >0.05).

Conclusion:

Our findings suggested that an appropriate intake of total zinc, iron, copper, selenium and magnesium were associated with lower CRC risk.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Nutr Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Nutr Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza