Refractory Graves' Disease in an Adolescent Successfully Treated With Cholestyramine and Subsequent Thyroidectomy.
Cureus
; 16(8): e66940, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-39280518
ABSTRACT
Graves' disease is the most common form of hyperthyroidism in children and adolescents. There are three primary lines of treatment for Graves' disease antithyroid drugs (ATDs), thyroidectomy, and radioactive iodine. Ideally, patients should be rendered euthyroid before surgery to minimize complications. Here, we report on a 14-year-old girl with severe Graves' disease refractory to conventional treatments despite maximal therapy over 18 months. The patient received two types of ATDs, beta-blockers, and different courses of steroids; however, her thyroid function tests remained high. She was then given an adjunctive four-week course of cholestyramine, to which she responded well and became euthyroid. Subsequently, a thyroidectomy was performed without complications. Cholestyramine is an effective adjunctive treatment for refractory Graves' disease in adolescents.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Cureus
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos