Concentrations, probabilistic human and ecological risks assessment attribute to antibiotics residues in river water in China: Systematic review and meta-analysis.
Ecotoxicol Environ Saf
; 285: 117022, 2024 Oct 15.
Article
en En
| MEDLINE
| ID: mdl-39277999
ABSTRACT
Antibiotics residues even low concentrations increases human health risk and ecological risk. The current study was conducted with the aims of meta-analysis concentrations of antibiotics in river water including amoxicillin (AMX), tetracyclines (TCN), sulfamethoxazole (SMX), ciprofloxacin (CIP), trimethoprim (TMP), azithromycin (AZM) and amoxicillin (AMX) and estimates human health and ecological risks. Search was performed in databases including Scopus, PubMed, Web of Science, Embase, Science direct, Cochrane, Science Direct, Google Scholar were used to retrieve scientific papers from January 1, 2004 to June 15, 2024. The concentration of antibiotics residues was meta-analyzed using random effects model in water river water based on type of antibiotics subgroups. Human health risk assessment from ingestion and dermal contact routs was estimated using target hazard quotient (THQ), total target hazard quotient (TTHQ), carcinogenic (CR) and ecological hazard quotient (EHQ) of antibiotics in river water was estimated using monte carlo simulations (MCS) model. Sixty-two papers on antibiotics in river water with 272 data-reports (n = 28,522) were included. The rank order of antibiotics residues in river water based on pooled concentration was SMX (66.086â¯ng/L) > CIP (26.005â¯ng/L) > TCN (17.888â¯ng/L) > TMP (6.591â¯ng/L) > AZM (2.077â¯ng/L) > AMX (0.029â¯ng/L). The overall pooled concentration of antibiotics residues in river water was 24.262â¯ng/L, 95â¯%CI (23.110-25.413â¯ng/L). TTHQ for adults and children due to antibiotics in water was 2.41E-3 and 2.36E-3, respectively. The sort of antibiotics based on their quota in TTHQ for adults and children was AMX > CIP > TMP > AZM > TCN > SMX. Total CR in adults and children was 2.41E-03 and 2.36E-03, respectively. The sort of antibiotics based on percentile 95â¯% EHQ was SMX (7.70E+03) > TCN (7.63E+01) > TMP (7.03E-03) > CIP (2.86E-03) > AMX (5.71E-04) and TEHQ values due to antibiotics in river water in China was equal to 7.78E+03. Current study suggests that conduct effective monitoring and water quality control plans to reduce concentration of antibiotics especially SMX, TCN, and CIP in river water of China.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Contaminantes Químicos del Agua
/
Ríos
/
Antibacterianos
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Países Bajos