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Quantifying the reproducibility and longitudinal repeatability of radiomics features in magnetic resonance Image-Guide accelerator Imaging: A phantom study.
Yu, Hang; Tang, Bin; Fu, Yuchuan; Wei, Weige; He, Yisong; Dai, Guyu; Xiao, Qing.
Afiliación
  • Yu H; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China.
  • Tang B; Department of Radiation Oncology, Radiation Oncology Key Laboratory Of Sichuan Province, Sichuan Cancer Hospital＆ Institute, Chengdu, Sichuan, China.
  • Fu Y; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China. Electronic address: ychfu@hotmail.com.
  • Wei W; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China.
  • He Y; Medical Physics Laboratory, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China.
  • Dai G; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China.
  • Xiao Q; Department of Radiotherapy Physics & Technology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, PR China.
Eur J Radiol ; 181: 111735, 2024 Sep 13.
Article en En | MEDLINE | ID: mdl-39276402
ABSTRACT

OBJECTIVE:

This study aimed to quantitatively evaluate the inter-platform reproducibility and longitudinal acquisition repeatability of MRI radiomics features in Fluid-Attenuated Inversion Recovery (FLAIR), T2-weighted (T2W), and T1-weighted (T1W) sequences on MR-Linac systems using an American College of Radiology (ACR) phantom. MATERIALS AND

METHODS:

This study used two MR-Linac systems (A and B) in different cancer centers. The ACR phantom was scanned on system A daily for 30 consecutive days to evaluate longitudinal repeatability. Additionally, retest data were collected after repositioning the phantom. Inter-platform reproducibility was assessed by conducting scans under identical conditions using system B. Regions of interest were delineated on the T1W sequence from system A and mapped to other sequences via rigid registration. Intra-observer and inter-observer comparisons were conducted. Repeatability and reproducibility were assessed using the intraclass correlation coefficient (ICC) and coefficient of variation (CV). Robust radiomics features were identified based on ICC>0.9 and CV<10 %.

RESULTS:

Analysis showed that a higher proportion of radiomics features derived from longitudinal FLAIR sequence (51.65 %) met robustness criteria compared to T2W (48.35 %) and T1W (43.96 %). Additionally, more inter-platform features from the FLAIR sequence (62.64 %) were robust compared to T2W (42.86 %) and T1W (39.56 %). Test-retest and intra-observer repeatability were excellent across all sequences, with a median ICC of 0.99 and CV<5%. However, inter-observer reproducibility was inferior, especially for the T1W sequence.

CONCLUSIONS:

Different sequences show variations in repeatability and reproducibility. The FLAIR sequence demonstrated advantages in both longitudinal repeatability and inter-platform reproducibility. Caution is warranted when interpreting data, particularly in longitudinal or multiplatform radiomics studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eur J Radiol Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eur J Radiol Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda