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Cardiovascular Risk in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review.
Sá-Sousa, Ana; Rodrigues, Cidália; Jácome, Cristina; Cardoso, João; Fortuna, Inês; Guimarães, Miguel; Pinto, Paula; Sarmento, Pedro Morais; Baptista, Rui.
Afiliación
  • Sá-Sousa A; MTG Research and Development Lab, 4200-604 Porto, Portugal.
  • Rodrigues C; Center for Health Technology and Services Research-CINTESIS@RISE, MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, 4200-450 Porto, Portugal.
  • Jácome C; Pulmonology Department, Unidade Local De Saúde de Coimbra, 3004-561 Coimbra, Portugal.
  • Cardoso J; MTG Research and Development Lab, 4200-604 Porto, Portugal.
  • Fortuna I; Center for Health Technology and Services Research-CINTESIS@RISE, MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, 4200-450 Porto, Portugal.
  • Guimarães M; Pulmonology Department, Unidade Local de Saúde São José, 1150-199 Lisboa, Portugal.
  • Pinto P; NOVA Medical School, Nova University Lisbon, 1169-056 Lisboa, Portugal.
  • Sarmento PM; MTG Research and Development Lab, 4200-604 Porto, Portugal.
  • Baptista R; Pulmonology Department, Unidade Local de Saúde de Gaia e Espinho, 4434-502 Vila Nova de Gaia, Portugal.
J Clin Med ; 13(17)2024 Aug 31.
Article en En | MEDLINE | ID: mdl-39274386
ABSTRACT
Background/

Objectives:

A comprehensive and up-to-date review on cardiovascular disease (CVD) risk in patients with COPD is needed. Therefore, we aimed to systematically review the risk of a range of CVD in patients with COPD.

Methods:

We searched three databases (Pubmed, Web of Science, SCOPUS) from inception to September 2023 using terms related to COPD and CVD. Observational studies were included if they (1) were conducted in adults with a diagnosis of COPD based on the GOLD criteria, spirometry, physician diagnosis, or review of electronic health records; (2) reported the risk of CVD, namely of myocardial infarction (MI), ischaemic heart disease (IHD), atrial fibrillation (AF), heart failure, cerebrovascular disease, pulmonary hypertension, and peripheral vascular disease, compared with a control population using a measure of risk. A narrative synthesis was used.

Results:

Twenty-four studies from 2015 to 2023, mainly from Europe (n = 17), were included. A total of 3,485,392 patients with COPD (43.5-76.0% male; 63.9-73.5 yrs) and 31,480,333 (40.0-55.4% male, 49.3-70.0 yrs) controls were included. A higher risk of CVD in patients with COPD was evident regarding overall CVD, MI, IHD, heart failure, and angina. Higher risks of arrhythmia and AF, stroke, sudden cardiac death/arrest, pulmonary embolism, pulmonary hypertension, and peripheral vascular disease were also found, although based on a small amount of evidence.

Conclusions:

Patients with COPD have a higher risk of CVD than the general population or matched controls. This review underscores the need for vigilant and close monitoring of cardiovascular risk in individuals with COPD to inform more precise preventive strategies and targeted interventions to enhance their overall management.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Suiza