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Effect of Silicon Nitride Coating on Titanium Surface: Biocompatibility and Antibacterial Properties.
Tani, Akina; Tsubouchi, Harumitsu; Ma, Lin; Taniguchi, Yurie; Kobayashi, Yasuyuki; Nakai, Mariko; Komasa, Satoshi; Hashimoto, Yoshiya.
Afiliación
  • Tani A; Department of Oral Health Sciences, Faculty of Health Sciences, Osaka Dental University, 1-4-4, Makino-honmachi, Hirakata-shi 573-1121, Osaka, Japan.
  • Tsubouchi H; Department of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi 573-1121, Osaka, Japan.
  • Ma L; Department of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi 573-1121, Osaka, Japan.
  • Taniguchi Y; Department of Anesthesiology, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi 573-1121, Osaka, Japan.
  • Kobayashi Y; Osaka Research Institute of Industrial Science and Technology, Morinomiya Center, 1-6-50, Morinomiya, Joto-ku, Osaka 536-8553, Osaka, Japan.
  • Nakai M; Department of Forensic Dentistry, Osaka Dental University, 8-1 Kuzuhahanazono-cho, Hirakata-shi 573-1121, Osaka, Japan.
  • Komasa S; Department of Oral Health Sciences, Faculty of Health Sciences, Osaka Dental University, 1-4-4, Makino-honmachi, Hirakata-shi 573-1121, Osaka, Japan.
  • Hashimoto Y; Department of Biomaterials, Osaka Dental University, 8-1 Kuzuhahanazono-cho, Hirakata-shi 573-1121, Osaka, Japan.
Int J Mol Sci ; 25(17)2024 Aug 23.
Article en En | MEDLINE | ID: mdl-39273096
ABSTRACT
In recent years, with the advent of a super-aged society, lifelong dental care has gained increasing emphasis, and implant therapy for patients with an edentulous jaw has become a significant option. However, for implant therapy to be suitable for elderly patients with reduced regenerative and immunological capabilities, higher osteoconductive and antimicrobial properties are required on the implant surfaces. Silicon nitride, a non-oxide ceramic known for its excellent mechanical properties and biocompatibility, has demonstrated high potential for inducing hard tissue differentiation and exhibiting antibacterial properties. In this study, silicon nitride was deposited on pure titanium metal surfaces and evaluated for its biocompatibility and antibacterial properties. The findings indicate that silicon nitride improves the hydrophilicity of the material surface, enhancing the initial adhesion of rat bone marrow cells and promoting hard tissue differentiation. Additionally, the antibacterial properties were assessed using Staphylococcus aureus, revealing that the silicon nitride-coated surfaces exhibited significant antibacterial activity. Importantly, no cytotoxicity was observed, suggesting that silicon nitride-coated titanium could serve as a novel implant material.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus / Propiedades de Superficie / Titanio / Compuestos de Silicona / Materiales Biocompatibles Revestidos / Antibacterianos Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus / Propiedades de Superficie / Titanio / Compuestos de Silicona / Materiales Biocompatibles Revestidos / Antibacterianos Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza