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Screening of Anisakis-Related Allergies and Associated Factors in a Mediterranean Community Characterized by High Seafood Consumption.
Fruscione, Santo; Barrale, Maria; Zarcone, Maurizio; Alba, Davide; Ravazzolo, Barbara; Belluzzo, Miriam; Onida, Rosa; Cammilleri, Gaetano; Costa, Antonella; Ferrantelli, Vincenzo; Savatteri, Alessandra; De Bella, Daniele Domenico; Pipitone, Salvatore; D'Atria, Alida; Pieri, Alessia; Tramuto, Fabio; Costantino, Claudio; Maida, Carmelo Massimo; Graziano, Giorgio; Palomba, Marialetizia; Mattiucci, Simonetta; Brusca, Ignazio; Mazzucco, Walter.
Afiliación
  • Fruscione S; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Barrale M; U.O.C. of Clinical Pathology Buccheri La Ferla Hospital FBF, 90123 Palermo, Italy.
  • Zarcone M; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Alba D; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Ravazzolo B; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Belluzzo M; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Onida R; U.O.C. of Clinical Pathology Buccheri La Ferla Hospital FBF, 90123 Palermo, Italy.
  • Cammilleri G; Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
  • Costa A; Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
  • Ferrantelli V; Experimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
  • Savatteri A; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • De Bella DD; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Pipitone S; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • D'Atria A; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Pieri A; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Tramuto F; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Costantino C; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Maida CM; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Graziano G; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Palomba M; PROMISE Department, University of Palermo, 90127 Palermo, Italy.
  • Mattiucci S; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Brusca I; U.O.C. Epidemiologia Clinica con Registro Tumori, Azienda Ospedaliera Universitaria Policlinico di Palermo, 90127 Palermo, Italy.
  • Mazzucco W; Department of Ecological and Biological Sciences, Tuscia University, 01100 Viterbo, Italy.
Foods ; 13(17)2024 Sep 05.
Article en En | MEDLINE | ID: mdl-39272586
ABSTRACT
Dietary changes expose consumers to risks from Anisakis larvae in seafood, leading to parasitic diseases and allergies. Anisakis is recognized by EFSA as a significant hazard, with potential oncogenic implications. Diagnostic advancements, like the Basophil Activation Test (BAT), enhance sensitivity and accuracy in identifying Anisakis sensitization, complementing traditional IgE tests. We conducted a cross-sectional study on patients with allergic symptoms from April 2021 to April 2023 at two outpatient clinics in western Sicily. Our goal was to assess the prevalence of Anisakis-related allergies and to identify risk profiles using specific Anisakis IgE and the BAT, especially in regions with high raw fish consumption. The study evaluated specific Anisakis IgE as a screening tool for Anisakis sensitization, using questionnaires, blood samples, and immuno-allergology analyses. Anisakis-specific IgE values were compared with the BAT results, with statistical analyses including Fisher's exact test and logistic regression. The results showed an 18.5% seroprevalence of Anisakis IgE, while the BAT as a second-level test showed 4.63%, indicating the BAT's superior specificity and accuracy. The study highlighted the importance of the BAT in diagnosing Anisakis sensitization, especially in cases of cross-reactivity with Ascaris and tropomyosin. The findings confirm the BAT's exceptional specificity in identifying Anisakis sensitization and support using Anisakis-specific IgE for population-based risk profiling. The BAT can effectively serve as a confirmatory test.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Foods Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Foods Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza