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Correlates of fentanyl preference among people who use drugs in Rhode Island.
Napoleon, Siena C; Park, Carolyn J; Goldman, Jacqueline; Li, Yu; Buxton, Jane A; Macmadu, Alexandria; Biello, Katie B; Noguchi, Julia; Marshall, Brandon D L.
Afiliación
  • Napoleon SC; Department of Behavioral and Social Health Sciences, Brown University School of Public Health, 121 South Main Street, Box G-S-121-3, Providence, RI, 02912, USA.
  • Park CJ; Department of Behavioral and Social Health Sciences, Brown University School of Public Health, 121 South Main Street, Box G-S-121-3, Providence, RI, 02912, USA.
  • Goldman J; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2 Providence, Providence, RI, 02912, USA.
  • Li Y; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2 Providence, Providence, RI, 02912, USA.
  • Buxton JA; School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada.
  • Macmadu A; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2 Providence, Providence, RI, 02912, USA.
  • Biello KB; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2 Providence, Providence, RI, 02912, USA.
  • Noguchi J; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2 Providence, Providence, RI, 02912, USA.
  • Marshall BDL; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S-121-2 Providence, Providence, RI, 02912, USA. brandon_marshall@brown.edu.
Harm Reduct J ; 21(1): 169, 2024 Sep 14.
Article en En | MEDLINE | ID: mdl-39272059
ABSTRACT

BACKGROUND:

Fentanyl is increasingly pervasive in the unregulated drug supply and is a driver of drug overdose deaths in the United States. The aims of this study were to characterize and identify correlates of fentanyl preference among people who use drugs (PWUD) in Rhode Island (RI).

METHODS:

Using bivariate analysis, we examined associations between fentanyl preference and sociodemographic and psychosocial characteristics at baseline among participants enrolled in the RI Prescription Drug and Illicit Drug Study from August 2020-February 2023. Fentanyl preference was operationalized based on responses to a five-point Likert scale "I prefer using fentanyl or drugs that have fentanyl in them." Participants who responded that they "strongly disagree," "disagree," or were "neutral" with respect to this statement were classified as not preferring fentanyl, whereas participants who responded that they "agree" or "strongly agree" were classified as preferring fentanyl.

RESULTS:

Among 506 PWUD eligible for inclusion in this analysis, 15% expressed a preference for fentanyl or drugs containing fentanyl as their drug of choice. In bivariate analyses, preference for fentanyl was positively associated with younger age, white race, lifetime history of overdose, history of injection drug use, past month enrollment in a substance use treatment program, past month treatment with medications for opioid use disorder, and preferences for heroin and crystal methamphetamine (all p < 0.05). Descriptive data yielded further insight into reasons for fentanyl preference, the predominant having to do with perceived effects of the drug and desire to avoid withdrawal symptoms.

CONCLUSIONS:

Only a relatively small subset of study participants preferred drugs containing fentanyl. Given the increased prevalence of fentanyl contamination across substances within the unregulated drug market, the result for PWUD is increasingly less agency with respect to choice of drug; for example, people may be forced to use fentanyl due to restricted supply and the need to mitigate withdrawal symptoms, or may be using fentanyl without intending to do so. Novel and more effective interventions for PWUD, including increased access to age-appropriate harm reduction programs such as fentanyl test strips and overdose prevention centers, are needed to mitigate fentanyl-related harms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fentanilo / Sobredosis de Droga Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Harm Reduct J Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fentanilo / Sobredosis de Droga Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Harm Reduct J Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido