Your browser doesn't support javascript.
loading
Ultrasound-measured Quadriceps Muscle Thickness and Mortality in Older Patients With Heart Failure.
Saito, Hiroshi; Fujimoto, Yudai; Matsue, Yuya; Yoshioka, Kenji; Maekawa, Emi; Kamiya, Kentaro; Toki, Misako; Iwata, Kentaro; Saito, Kazuya; Murata, Azusa; Hayashida, Akihiro; Ako, Junya; Kitai, Takeshi; Kagiyama, Nobuyuki.
Afiliación
  • Saito H; Department of Rehabilitation, Kameda Medical Center, Kamogawa, Japan.
  • Fujimoto Y; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Matsue Y; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan. Electronic address: yuya8950@gmail.com.
  • Yoshioka K; Department of Cardiology, Kameda Medical Center, Kamogawa, Japan.
  • Maekawa E; Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
  • Kamiya K; Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.
  • Toki M; Department of Clinical Laboratory, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Iwata K; Department of Rehabilitation, Kobe City Medical Center General Hospital, Kobe, Japan.
  • Saito K; Department of Rehabilitation, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Murata A; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Hayashida A; Department of Cardiology, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
  • Ako J; Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
  • Kitai T; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Centre, Osaka, Japan.
  • Kagiyama N; Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Cardiology, The Sakakibara Heart Institute of Okayama, Okayama, Japan.
Can J Cardiol ; 2024 Sep 11.
Article en En | MEDLINE | ID: mdl-39270750
ABSTRACT

BACKGROUND:

Ultrasound might be helpful for muscle mass assessment in patients with heart failure (HF). We aimed to determine the feasibility and prognostic implications of ultrasound-measured quadriceps muscle thickness (QMT) in older patients with HF.

METHODS:

This was a post hoc analysis of a multicentre prospective cohort study including patients hospitalized for HF aged 65 years and older. QMT at rest and during isometric contractions using ultrasound was measured with the patient in the supine position before discharge.

RESULTS:

The interobserver agreement for measuring QMT was excellent, with intraclass correlation coefficients of 0.979 (95% confidence interval [CI], 0.963-0.988) at rest and 0.997 (95% CI, 0.994-0.998) during isometric contraction. The intraobserver reproducibility was also excellent (intraclass correlation coefficient > 0.92). Of the 595 patients (median age, 81 years; 56% male), median QMT at rest and during contraction were 18.9 mm and 24.9 mm, respectively. The patients were grouped according to sex-specific tertiles of height-adjusted QMT. During the median follow-up of 735 days, 157 deaths occurred, and Kaplan-Meier curve analysis showed that the lowest tertile of the height-adjusted QMT was associated with a higher mortality. Cox proportional hazard analysis revealed that thinner height-adjusted QMT was independently associated with higher mortality, even after adjusting for conventional risk factors (per 1 mm/m increase hazard ratio, 0.94; 95% CI, 0.89-0.99; P = 0.030 [at rest] and hazard ratio, 0.94; 95% CI, 0.90-0.99; P = 0.015 [during isometric contraction]).

CONCLUSIONS:

Ultrasound-measured QMT in older patients with HF is feasible, and thinner height-adjusted QMT at rest and during isometric contraction was independently associated with higher mortality.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Can J Cardiol Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Can J Cardiol Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido