Your browser doesn't support javascript.
loading
Patch-free streaming contrast-rebalanced dichoptic cartoons versus patching for treatment of amblyopia in children aged 3 to 5 years: a pilot, randomized clinical trial.
Jost, Reed M; Birch, Eileen E; Wang, Yi-Zhong; Dao, Lori M; Stager, David; Luu, Becky; Beauchamp, Cynthia L; Giridhar, Prashanthi; Brin, Taylor A; Baldwin, Alex S; Hess, Robert F; Thompson, Benjamin.
Afiliación
  • Jost RM; Pediatric Vision Laboratory, Retina Foundation of the Southwest, Dallas, Texas. Electronic address: reedjost@retinafoundation.org.
  • Birch EE; Pediatric Vision Laboratory, Retina Foundation of the Southwest, Dallas, Texas; Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Wang YZ; Pediatric Vision Laboratory, Retina Foundation of the Southwest, Dallas, Texas; Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Dao LM; ABC Eyes - Pediatric Ophthalmology, Dallas, Texas.
  • Stager D; Pediatric Ophthalmology & Adult Strabismus, Plano, Texas.
  • Luu B; Pediatric Ophthalmology & Adult Strabismus, Plano, Texas.
  • Beauchamp CL; ABC Eyes - Pediatric Ophthalmology, Dallas, Texas.
  • Giridhar P; ABC Eyes - Pediatric Ophthalmology, Dallas, Texas.
  • Brin TA; School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada; Department of Human Sciences, Kanagawa University, Yokohama, Kanagawa, Japan.
  • Baldwin AS; Department of Ophthalmology, McGill University, Montreal, Quebec, Canada.
  • Hess RF; Department of Ophthalmology, McGill University, Montreal, Quebec, Canada.
  • Thompson B; School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada; Centre for Eye and Vision Research, 17W Science Park, Hong Kong; Liggins Institute, University of Auckland, Auckland, New Zealand.
J AAPOS ; 28(5): 103991, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39270746
ABSTRACT

BACKGROUND:

We developed and tested a dichoptic treatment designed for younger children that can be viewed freely and involves a dichoptic manipulation of a popular animation series that enables contrast-rebalancing without disrupting fusion. Our aim was to assess whether this novel amblyopia treatment is superior to patching in children aged 3-5 years.

METHODS:

A total of 34 children with amblyopia were randomly assigned to contrast-rebalanced dichoptic cartoons (4 hours/week) or patching (14 hours/week) for 2 weeks. Children in the cartoon group continued watching cartoons for an additional 2 weeks. Designed to target the youngest and most treatable children, the dichoptic cartoons presented the entire scene to the amblyopic eye at 100% contrast, while the fellow eye view was presented at reduced contrast with the main character omitted. Best-corrected visual acuity (BCVA), stereoacuity, suppression, and manual dexterity were measured at each visit.

RESULTS:

After 2 weeks, improvement in amblyopic eye BCVA was greater for dichoptic treatment than for patching, with a mean improvement of 0.11 ± 0.08 versus 0.06 ± 0.09 logMAR, respectively (P = 0.04). Stereoacuity, suppression, and manual dexterity did not improve significantly more in the dichoptic group than the patching group at 2 weeks. After 4 weeks of dichoptic cartoon treatment, mean visual acuity improvement in the dichoptic group was 0.16 logMAR (95% CI, 0.10-0.21).

CONCLUSIONS:

In our study cohort, a contrast-rebalanced dichoptic cartoon was more effective than patching in treating childhood amblyopia after 2 weeks. Dichoptic cartoons that rebalance contrast to overcome suppression provide an additional treatment option for amblyopia in young children.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Privación Sensorial / Visión Binocular / Agudeza Visual / Ambliopía Límite: Child, preschool / Female / Humans / Male Idioma: En Revista: J AAPOS Asunto de la revista: OFTALMOLOGIA / PEDIATRIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Privación Sensorial / Visión Binocular / Agudeza Visual / Ambliopía Límite: Child, preschool / Female / Humans / Male Idioma: En Revista: J AAPOS Asunto de la revista: OFTALMOLOGIA / PEDIATRIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos