Your browser doesn't support javascript.
loading
Advances in microbial production of geraniol: from metabolic engineering to potential industrial applications.
Wang, Xun; Zhang, Xinyi; Zhang, Jia; Zhou, Yujunjie; Wang, Fei; Wang, Zhiguo; Li, Xun.
Afiliación
  • Wang X; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry
  • Zhang X; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry
  • Zhang J; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry
  • Zhou Y; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry
  • Wang F; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry
  • Wang Z; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing, China.
  • Li X; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Provincial Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering, Nanjing Forestry
Crit Rev Biotechnol ; : 1-16, 2024 Sep 12.
Article en En | MEDLINE | ID: mdl-39266251
ABSTRACT
Geraniol, an acyclic monoterpene alcohol, has significant potential applications in various fields, including food, cosmetics, biofuels, and pharmaceuticals. However, the current sources of geraniol mainly include plant tissue extraction or chemical synthesis, which are unsustainable and suffer severely from high energy consumption and severe environmental problems. The process of microbial production of geraniol has recently undergone vigorous development. Particularly, the sustainable construction of recombinant Escherichia coli (13.2 g/L) and Saccharomyces cerevisiae (5.5 g/L) laid a solid foundation for the microbial production of geraniol. In this review, recent advances in the development of geraniol-producing strains, including metabolic pathway construction, key enzyme improvement, genetic modification strategies, and cytotoxicity alleviation, are critically summarized. Furthermore, the key challenges in scaling up geraniol production and future perspectives for the development of robust geraniol-producing strains are suggested. This review provides theoretical guidance for the industrial production of geraniol using microbial cell factories.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Crit Rev Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Crit Rev Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido