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Mitochondrial Function and Resistance to Oxidative Stress in the Kidney during Pregnancy.
Popkov, V A; Buyan, M I; Makievskaya, K I; Brezgunova, A A; Pevzner, I B; Zorova, L D; Zorov, D B; Plotnikov, E Yu; Andrianova, N V.
Afiliación
  • Popkov VA; A. N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia. popkov@belozersky.msu.ru.
  • Buyan MI; Institute for Artificial Intelligence, Lomonosov Moscow State University, Moscow, Russia. popkov@belozersky.msu.ru.
  • Makievskaya KI; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
  • Brezgunova AA; Institute for Artificial Intelligence, Lomonosov Moscow State University, Moscow, Russia.
  • Pevzner IB; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
  • Zorova LD; A. N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
  • Zorov DB; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
  • Andrianova NV; A. N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Bull Exp Biol Med ; 2024 Sep 12.
Article en En | MEDLINE | ID: mdl-39264559
ABSTRACT
We demonstrated that the serum of pregnant rats increases viability of kidney epithelial cells and promotes their proliferation. The intensity of oxidative stress in the kidneys was also reduced during pregnancy, but only in rats that were not exposed to acute ischemic kidney injury. This decrease in oxidative stress was not associated with changes in transmembrane mitochondrial potential, the size of mitochondria, time of opening of mitochondrial permeability transition pore (mPTP), mitochondrial respiration rate, antioxidant activity, or nitric oxide level.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bull Exp Biol Med Año: 2024 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bull Exp Biol Med Año: 2024 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos