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Factors Associated With Improvement Following In-office Steroid Injections for Vocal Fold Scar.
Tesema, Naomi; Lackey, Taylor G; O'Connor, Mackenzie; Kwak, Paul E; Johnson, Aaron M; Amin, Milan R.
Afiliación
  • Tesema N; NYU Langone Health, New York, New York, U.S.A.
  • Lackey TG; NYU Langone Health, New York, New York, U.S.A.
  • O'Connor M; NYU Langone Health, New York, New York, U.S.A.
  • Kwak PE; NYU Langone Health, New York, New York, U.S.A.
  • Johnson AM; NYU Langone Health, New York, New York, U.S.A.
  • Amin MR; NYU Langone Health, New York, New York, U.S.A.
Laryngoscope ; 2024 Sep 12.
Article en En | MEDLINE | ID: mdl-39264157
ABSTRACT

OBJECTIVE:

This study aims to evaluate the clinical outcomes of patients receiving in-office vocal fold steroid injections (VFSI), highlighting relatively new measures around vocal pitch.

METHODS:

Patients with a diagnosis of vocal fold scar who received in-office VFSI from 2013 to 2024 were evaluated. Pre- and post-steroid Voice Handicap Index (VHI-10) scores, stroboscopic vibratory parameters, acoustic measures of cepstral peak prominence (CPP), and fundamental frequency coefficient of variation (F0CoV) during sustained phonation were analyzed using Wilcoxon signed-rank tests and McNemar's tests.

RESULTS:

Twenty-two patients had follow-up data 1-3 months after steroid injection. The median decrease in VHI-10 after one injection was 4 points (p = 0.02). We found no difference in CPP and F0CoV measures at follow-up. Forty-five percent of patients improved in mucosal wave and amplitude of at least one vocal fold. Earlier presentation from vocal injury was associated with improvement in mucosal wave and amplitude of the left vocal fold (p = 0.03). We found no difference in sex, tobacco smoking history, singing status, secondary diagnosis, and baseline VHI-10 score between patients who improved in vibratory parameters and those who did not.

CONCLUSION:

This single-center study is one of the largest exploring patient outcomes following in-office VFSI. Though patients reported modest improvement in voice use after VFSI, this may not be as impactful as previously believed. Improvement in videostroboscopy is expected in about half of the patients, with recency from vocal injury a likely predictor of success. These partially negative results provide insight into counseling patients regarding benefits from in-office VFSI. LEVEL OF EVIDENCE 4 Laryngoscope, 2024.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos