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The impacts of physical factors on huge hepatocellular carcinoma treated by transarterial chemoembolization combined with radiotherapy.
Shen, Juanjuan; Zhong, Nanbao; Chen, Zhonghua; Ma, Danyu; Lin, Jianhai.
Afiliación
  • Shen J; Department of Tumor Radiotherapy, 900th Hospital of PLA, Fuzhou, China.
  • Zhong N; Department of Tumor Radiotherapy, 900th Hospital of PLA, Fuzhou, China.
  • Chen Z; Department of Tumor Radiotherapy, 900th Hospital of PLA, Fuzhou, China.
  • Ma D; Department of Tumor Radiotherapy, 900th Hospital of PLA, Fuzhou, China.
  • Lin J; Department of Tumor Radiotherapy, 900th Hospital of PLA, Fuzhou, China.
Future Oncol ; : 1-11, 2024 Sep 12.
Article en En | MEDLINE | ID: mdl-39263953
ABSTRACT

Aims:

To assess the influence of various physical factors on the outcome of transarterial chemoembolization combined with γ-ray hypofractionated radiation therapy (TACE-γHRT) for unresectable huge (≥10 cm) hepatocellular carcinoma (UH-HCC) patients.Materials &

methods:

A total of 162 UH-HCC patients with different tumor locations treated with TACE-γHRT and a retrospective analysis was conducted to evaluate the impacts of selected physical parameters on clinical outcomes.

Results:

The selected physical factors influenced the clinical outcomes significantly. No adverse events exceeding grade 3 were observed in the enrolled patients.

Conclusion:

Higher P70 and marginal dose, smaller tumor size and tumor location of neither skin nor gastrointestinal tracts involved were independent predictors for better overall survival and progression free survival.
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Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Future Oncol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Future Oncol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido