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Understanding the role of biomolecular coronas in human exposure to nanomaterials.
Soliman, Mahmoud G; Martinez-Serra, Alberto; Antonello, Giulia; Dobricic, Marko; Wilkins, Terence; Serchi, Tommaso; Fenoglio, Ivana; Monopoli, Marco P.
Afiliación
  • Soliman MG; Chemistry Department, RCSI (Royal College of Surgeons in Ireland) 123 St Stephen Green Dublin 2 Ireland mahmoudsoliman@rcsi.ie marcomonopoli@rcsi.ie.
  • Martinez-Serra A; Physics Department, Faculty of Science, Al-Azhar University Cairo Egypt.
  • Antonello G; Chemistry Department, RCSI (Royal College of Surgeons in Ireland) 123 St Stephen Green Dublin 2 Ireland mahmoudsoliman@rcsi.ie marcomonopoli@rcsi.ie.
  • Dobricic M; Department of Chemistry, University of Torino 10125 Torino Italy.
  • Wilkins T; Chemistry Department, RCSI (Royal College of Surgeons in Ireland) 123 St Stephen Green Dublin 2 Ireland mahmoudsoliman@rcsi.ie marcomonopoli@rcsi.ie.
  • Serchi T; School of Chemical & Process Innovation, University of Leeds Engineering Building Leeds LS2 9JT UK.
  • Fenoglio I; Environmental Research and Innovation Department (Luxembourg Institute of Science and Technology) 41, Rue du Brill L4422 Belvaux GD Luxembourg.
  • Monopoli MP; Department of Chemistry, University of Torino 10125 Torino Italy.
Environ Sci Nano ; 11(11): 4421-4448, 2024 Nov 07.
Article en En | MEDLINE | ID: mdl-39263008
ABSTRACT
Nanomaterials (NMs) are increasingly used in medical treatments, electronics, and food additives. However, nanosafety-the possible adverse effects of NMs on human health-is an area of active research. This review provides an overview of the influence of biomolecular coronas on NM transformation following various exposure routes. We discuss potential exposure pathways, including inhalation and ingestion, describing the physiology of exposure routes and emphasising the relevance of coronas in these environments. Additionally, we review other routes to NM exposure, such as synovial fluid, blood (translocation and injection), dermal and ocular exposure, as well as the dose and medium impact on NM interactions. We emphasize the need for an in-depth characterisation of coronas in different biological media, highlighting the need and opportunity to study lung and gastric fluids to understand NM behaviour and potential toxicity. Future research aims to predict better in vivo outcomes and address the complexities of NM interactions with biological systems.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Environ Sci Nano Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Environ Sci Nano Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido