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Controlling Nutritional Status Score Predicts 1-Year Outcomes in Chronic Thromboembolic Pulmonary Hypertension.
Adachi, Takeshi; Adachi, Shiro; Nakano, Yoshihisa; Nishiyama, Itsumure; Hirose, Miku; Murohara, Toyoaki.
Afiliación
  • Adachi T; Department of Cardiology, Nagoya University Hospital Nagoya Japan.
  • Adachi S; Department of Cardiology, Nagoya University Hospital Nagoya Japan.
  • Nakano Y; Center for Advanced Medicine and Clinical Research, Department of Advanced Medicine, Nagoya University Hospital Nagoya Japan.
  • Nishiyama I; Department of Cardiology, Nagoya University Graduate School of Medicine Nagoya Japan.
  • Hirose M; Department of Cardiology, Nagoya University Graduate School of Medicine Nagoya Japan.
  • Murohara T; Department of Cardiology, Nagoya University Hospital Nagoya Japan.
Circ Rep ; 6(9): 381-388, 2024 Sep 10.
Article en En | MEDLINE | ID: mdl-39262638
ABSTRACT

Background:

The prognosis for patients with chronic thromboembolic pulmonary hypertension (CTEPH) using their nutritional status has not been established. We investigated the relationship between the prognosis of patients with CTEPH and the Controlling Nutritional Status (CONUT) score, which is a nutritional assessment tool. Methods and

Results:

A total of 157 patients with CTEPH was enrolled in the study. The primary outcome was defined as the composite outcome of all-cause mortality and non-elective hospitalization due to heart failure. Receiver operating characteristic (ROC) curve analysis was used to determine the cutoff CONUT score for predicting the 1-year rate of the primary outcome. Patients were divided into 2 groups according to the significant cutoff value and compared. Undernutrition was observed in 51.6% of patients. ROC analysis revealed a significant cutoff CONUT score of 3.5 (area under the curve=0.789). The incidence rate of the primary composite outcome was higher in the high CONUT group (score ≥4) than in the low CONUT group (score ≤3; 20% vs. 2.2%; P<0.001). Cox analysis revealed the CONUT score per point increase was an independent risk factor for the primary composite outcomes (hazard ratio 2.301; 95% confidence interval 1.081-4.895; P=0.031).

Conclusions:

The CONUT score can predict the 1-year rate of all-cause death and non-elective hospitalization in patients with CTEPH.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Circ Rep Año: 2024 Tipo del documento: Article Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Circ Rep Año: 2024 Tipo del documento: Article Pais de publicación: Japón