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Safety evaluation of extracorporeal shockwave lithotripsy for pancreatic stones: Experience based on a large chronic pancreatitis cohort.
Liu, Yu; Yi, Jin-Hui; Wang, Peng-Yuan; Fu, Peng; Kang, Ying; Wang, Teng; Zhang, Di; Zhang, Xi-Hong; Xu, Jin-Jie; Zhang, Song-Lin; Han, Pei-Dong; Wang, Fan; Zhou, Xiao-Yu; Feng, Jia-Sheng; Xu, Jia-Jun; Qian, Jia-Hao; Wang, Dan; Chen, Hui; Liu, Run-Hui; Wang, Fang-Yu; Li, Zhao-Shen; Hu, Liang-Hao.
Afiliación
  • Liu Y; Department of Gastroenterology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, Jiangsu, China; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical Univer
  • Yi JH; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Wang PY; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China; Department of Gastroenterology, the 981st H
  • Fu P; Department of Pharmacy, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
  • Kang Y; Department of Gastroenterology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, Jiangsu, China.
  • Wang T; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Zhang D; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Zhang XH; Department of Gastroenterology, The Second Hospital of Shandong University, Jinan, 250012, Shandong, China; Department of Critical Care Medicine, Liaocheng People's Hospital, Liaocheng, 252000, Shandong, China.
  • Xu JJ; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Zhang SL; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Han PD; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Wang F; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Zhou XY; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Feng JS; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Xu JJ; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Qian JH; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Wang D; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Chen H; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China.
  • Liu RH; Department of Pharmacology, College of Pharmacy, Naval Medical University, Shanghai, 200433, China. Electronic address: lyliurh@126.com.
  • Wang FY; Department of Gastroenterology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, Jiangsu, China. Electronic address: wangfy65@nju.edu.cn.
  • Li ZS; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China. Electronic address: zhaoshen-li@hotmail.com
  • Hu LH; Department of Gastroenterology, Changhai Clinical Research Unit, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China; Shanghai Institute of Pancreatic Diseases, Shanghai, 200433, China. Electronic address: lianghao-hu@smmu.edu.cn
Dig Liver Dis ; 2024 Sep 10.
Article en En | MEDLINE | ID: mdl-39261265
ABSTRACT

BACKGROUND:

The safety of extracorporeal shock wave lithotripsy for pancreatic stones (P-ESWL) and adverse events were not evaluated and classified within large sample population. This study aimed to evaluate the safety and classify the adverse events of P-ESWL based on a large sample cohort.

METHODS:

This is an observational study based on the large prospective chronic pancreatitis (CP) cohort. Patients with painful pancreatic stones over 5 mm who underwent P-ESWL between March 2011 and June 2018 at Shanghai Changhai Hospital were included. Adverse events after P-ESWL including complications and transient adverse events (TAEs) were recorded. Risk factors of adverse events were analyzed through univariable and multivariable logistics regression analysis. Sensitivity analysis was conducted to test the stability of the study.

RESULTS:

Totally 2,071 patients underwent 5,002 sessions of P-ESWL were included. The overall complication rate and TAEs rate after all P-ESWL procedures were 5.2% and 20.9%. The complications and TAEs rate decreased obviously within the first 6 sessions. Several independent risk factors for adverse events after P-ESWL were identified. Sensitivity analysis suggested the stability of the results.

CONCLUSIONS:

P-ESWL is a safe treatment for pancreatic stones. Multiple P-ESWL sessions did not increase the complications and TAEs rate. ClincialTrials.gov number, NCT05916547.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Dig Liver Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Dig Liver Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos