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Radiosynoviorthesis with [90Y] Yttrium citrate in refractory synovitis of the knee: Experience of 2 reference hospitals.
Bolívar Roldán, I; Moreno Ballesteros, Ana; Martínez Chinchilla, C; Jiménez-Heffernan, A; Calvo Morón, M C.
Afiliación
  • Bolívar Roldán I; Unidad de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, Spain. Electronic address: isagranada1518@gmail.com.
  • Moreno Ballesteros A; Unidad de Medicina Nuclear, Hospital Universitario Juan Ramón Jiménez, Huelva, Spain.
  • Martínez Chinchilla C; Unidad de Hematología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.
  • Jiménez-Heffernan A; Unidad de Medicina Nuclear, Hospital Universitario Juan Ramón Jiménez, Huelva, Spain.
  • Calvo Morón MC; Unidad de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Rev Esp Med Nucl Imagen Mol (Engl Ed) ; : 500052, 2024 Sep 10.
Article en En | MEDLINE | ID: mdl-39260802
ABSTRACT

INTRODUCTION:

To describe the therapeutic efficacy of radiosynoviorthesis with [90Y]Yttrium citrate (90Y), in patients with chronic knee synovitis refractory to systemic treatments and/or infiltrations, correlating the results with the different etiologies and degenerative changes that they showed, in order to optimize the indication of the technique. MATERIAL AND

METHODS:

Observational retrospective study with 32 patients (22 men and 10 women) and 34 knees, with refractory chronic knee synovitis, who underwent radiosynoviorthesis between January 2013 and December 2022. Its efficacy was described and analyzed by the subjective improvement referred by the patients and its relationship with the existing etiologies and radiological degenerative changes, expressed by the Kellgren-Lawrence (K-L) scale.

RESULTS:

A statistically significant subjective improvement was observed in 70.6% of the cases (p < 0.001). There were 92.3% of cases with absent, doubtful or mild degenerative changes (K-L 0-2) who improved, while only 50% with moderate or severe changes (K-L 3-4) improved, showing statistically significant differences (p = 0.03). Among patients with chronic inflammatory origin of synovitis (spondyloarthropathies and rheumatoid arthritis), 80% improved, while in those with osteoarthritis (degenerative) origin, only 25% improved with statistically significant differences (p = 0.006).

CONCLUSIONS:

Radiosynoviorthesis with 90Y is an effective treatment in patients with knee refractory chronic synovitis, especially in the presence of mil degenerative joint changes and chronic inflammatory origin. We must ensure the appropiate selection of patients according to these criteria.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Rev Esp Med Nucl Imagen Mol (Engl Ed) Año: 2024 Tipo del documento: Article Pais de publicación: España
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Rev Esp Med Nucl Imagen Mol (Engl Ed) Año: 2024 Tipo del documento: Article Pais de publicación: España