Radiological changes in the thymus in patients who have had COVID-19 and in vaccinated persons who have not had COVID-19: a CT study.
Radiologie (Heidelb)
; 2024 Sep 11.
Article
en En
| MEDLINE
| ID: mdl-39259290
ABSTRACT
BACKGROUND:
There are very few and limited studies on the role of the thymus in COVID-19 infection. It is known that thymus morphology changes in individuals vaccinated against COVID-19 although they do not have active infection.OBJECTIVE:
Our study aims to evaluate these differences in detail.METHODS:
This research was conducted in a total of 141 people, 75 women and 66 men. The research consisted of three groups unvaccinated persons who have had the disease (nâ¯= 49), vaccinated persons who have not had the disease (nâ¯= 37), and unvaccinated persons who have not had the disease (control group, nâ¯= 55). In the study, the thymus volume, structure, and fat content were investigated and the differences between groups were evaluated.RESULTS:
Thymus volume was greatest (0.43⯱ 0.11) in the vaccinated group that had not had the disease and smallest (0.15⯱ 0.07) in the unvaccinated group that had had the disease, and a significant difference was found between the groups. Thymus steatosis was seen mostly in the unvaccinated group that had had the disease (72%; pâ¯= 0.04). The diffuse nodular pattern was only present in the diseased group.CONCLUSION:
This research is the first study in the literature to date on the effect of COVID-19 and vaccines on the thymus. In addition to the acute consequences of the virus, the possibility of negative symptoms after COVID-19 should also be kept in mind, especially in unvaccinated people. Further studies are needed to confirm the results reported herein.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Radiologie (Heidelb)
Año:
2024
Tipo del documento:
Article
País de afiliación:
Turquía
Pais de publicación:
Alemania