Your browser doesn't support javascript.
loading
Giant laryngeal neuroendocrine neoplasm causing airway obstruction: A case report and literature review.
Wang, Yaqi; Ding, Longqing; Liu, Jiahui; Guo, Ying; Yao, Yisong; Chen, Xi; Mou, Yakui; Song, Xicheng.
Afiliación
  • Wang Y; Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai Yuhuangding Hospital, Qingdao University, Yantai, P. R. China.
  • Ding L; Department of Otolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, P. R. China.
  • Liu J; School of Clinical Medicine, Shandong Second Medical University, Weifang, P. R. China.
  • Guo Y; Department of Otorhinolaryngology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Ji'nan, P. R. China.
  • Yao Y; Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai Yuhuangding Hospital, Qingdao University, Yantai, P. R. China.
  • Chen X; Department of Otolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, P. R. China.
  • Mou Y; Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai Yuhuangding Hospital, Qingdao University, Yantai, P. R. China.
  • Song X; Department of Otolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, P. R. China.
Medicine (Baltimore) ; 103(22): e38382, 2024 May 31.
Article en En | MEDLINE | ID: mdl-39259067
ABSTRACT
RATIONALE Laryngeal neuroendocrine neoplasm (NEN) is a rare and heterogeneous disease that originates from neuroendocrine cells. It mainly occurs in middle-aged and elderly men. Due to the lack of specific clinical and imaging manifestations, diagnosis and treatment of the disease pose a challenge. Therefore, a consensus on the diagnosis and treatment of the disease is necessary. By discussing this case, we will be able to gain further insight into laryngeal NEN and will be able to provide some recommendations for the future management of this rare disease. PATIENT CONCERNS A 67-year-old man was admitted to our department with a history of sore throat and dyspnea. After admission, the patient experienced acute airway obstruction and experienced an emergency bedside tracheotomy. DIAGNOSES Flexible fiberoptic laryngoscopy and enhanced CT showed a cauliflower-like mass in the left supraglottic region and obstructed most of the laryngeal cavity. We biopsied the mass, and the pathology showed a poorly differentiated adenocarcinoma.

INTERVENTIONS:

A horizontal hemilaryngectomy and left neck dissection were performed. At 4 weeks after the operation, the patient underwent chemotherapy and radical radiotherapy.

OUTCOMES:

After a 1-year postoperative follow-up, the patient recovered well and showed no signs of recurrence. LESSONS Laryngeal neuroendocrine neoplasm is very rare, early diagnosis remains difficult. Radical surgery combined with postoperative chemoradiotherapy is currently the most appropriate treatment.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Laríngeas / Tumores Neuroendocrinos / Obstrucción de las Vías Aéreas Límite: Aged / Humans / Male Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Laríngeas / Tumores Neuroendocrinos / Obstrucción de las Vías Aéreas Límite: Aged / Humans / Male Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos