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Ivabradine and Milrinone-Bridge to Recovery in New HFrEF With Low-Output Heart Failure.
Racharla, Lekha; Gitzel, Lucas; Joseph, Max; Guthier, Desire; Hawwa, Nael.
Afiliación
  • Racharla L; Lehigh Valley Heart and Vascular Institute Lehigh Valley Health Network, Allentown, Pennsylvania, USA.
  • Gitzel L; Department of Internal Medicine Lehigh Valley Health Network, Allentown, Pennsylvania, USA.
  • Joseph M; Morsani College of Medicine University of South Florida Health, Tampa, Florida, USA.
  • Guthier D; Department of Cardiovascular Medicine University of Florida, Gainesville, Florida, USA.
  • Hawwa N; Lehigh Valley Heart and Vascular Institute Lehigh Valley Health Network, Allentown, Pennsylvania, USA.
Case Rep Cardiol ; 2024: 5278240, 2024.
Article en En | MEDLINE | ID: mdl-39257453
ABSTRACT
In patients with newly diagnosed heart failure with reduced ejection fraction (HFrEF) who are on a downward clinical trajectory, options are mostly limited to left ventricular assist device and transplantation. However, in those with factors favorable for reverse remodeling, every effort should be made to promote native myocardial recovery. We present three patients with newly diagnosed severe HFrEF, NYHA Class 3-4 symptoms, and low cardiac output with and without organ malperfusion. Ivabradine and/or home milrinone were used during their tenuous hemodynamic period as a bridge to optimize guideline-directed medical therapy (GDMT), device therapy, and eventual reverse remodeling. Evidence of structural heart improvement continued far beyond 1 year.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Case Rep Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Case Rep Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos