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Diurnal changes of corneal epithelial and stromal thickness maps and visual quality in mild form of Fuchs' endothelial corneal dystrophy.
Krolo, Iva; Kasumovic Becirevic, Aida; Radman, Ivana; Kasumovic, Armin; Matoc, Ines; Goñi Guarro, Idoia; Sabol, Ivan.
Afiliación
  • Krolo I; University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Vinogradska cesta 29, Zagreb, Croatia.
  • Kasumovic Becirevic A; Department of Medicine and Pharmacology, Vrije Universiteit Brussel (VUB), Bd de la Plaine 2, Brussels, Belgium.
  • Radman I; Oftalmología Médica y Quirúrgica (OMIQ) Research, Servicio de Oftalmología, C/de Londres, 38, 1° planta, Eixample, Barcelona, Spain.
  • Kasumovic A; University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Vinogradska cesta 29, Zagreb, Croatia.
  • Matoc I; Department of Ophthalmology, Eye Polyclinic Dr. Sefic, Ferhadija 5, Sarajevo, Bosnia and Herzegovina.
  • Goñi Guarro I; University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Vinogradska cesta 29, Zagreb, Croatia.
  • Sabol I; University Department of Ophthalmology, University Hospital Center Sestre milosrdnice, Vinogradska cesta 29, Zagreb, Croatia.
Indian J Ophthalmol ; 2024 Sep 10.
Article en En | MEDLINE | ID: mdl-39257077
ABSTRACT

PURPOSE:

To investigate the functional and structural daily variations in eyes with a mild form of Fuchs' endothelial corneal dystrophy (FECD).

METHODS:

This prospective study included 30 eyes with the mild form of FECD. Subjects underwent functional and structural testing at 8 AM, 2 PM, and 8 PM. Testing included measurement of uncorrected distance visual acuity (UDVA), best corrected twilight vision (TV), and contrast sensitivity function (CSF) testing (Vista Vision Far-Pola, DMD MedTech charts). Corneal epithelial and stromal parameters were evaluated with anterior segment optical coherence tomography (AngioVue, AvantiRTVue-XR; Optovue, CA, USA).

RESULTS:

UDVA, TV, and CSF for spatial frequencies B, C, and F showed significant changes during the day, with the lowest values in the morning (P < 0.0001 for UDVA, P = 0.0109 for TV, and P < 0.0001, P = 0.0126, and P = 0.0471 for the three spatial frequencies, respectively). There was no significant change in epithelial parameters between visits. Central corneal thickness showed significant decrease during the day (P < 0.0001), as did the central stromal thickness on the 5- and 7-mm maps (P = 0.0002 and P < 0.0001, respectively), stromal thickness in the superior section of the 5-mm map (P = 0.0107), stromal thickness in the inferior section of the 7-mm map (P = 0.0002), and minimal stromal thickness on both maps (P < 0.0001).

CONCLUSION:

A significant negative correlation was found between central stromal thickness and TV, implying that simultaneous evaluation of corneal layers and visual quality may be useful in assessing FECD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Ophthalmol Año: 2024 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Ophthalmol Año: 2024 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: India