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The White Blood Cell Count in Laboring Women at Term Is Associated with Neonatal Macrosomia.
Srebnik, Naama; Michaeli, Jennia; Ruchlemer, Rosa; Farkash, Rivka; Rotshenker-Olshinka, Keren; Grisaru-Granovsk, Sorina.
Afiliación
  • Srebnik N; Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University School of Medicine, Jerusalem, Israel.
  • Michaeli J; Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University School of Medicine, Jerusalem, Israel.
  • Ruchlemer R; Department of Hematology, Shaare Zedek Medical Center, Jerusalem, Israel.
  • Farkash R; Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University School of Medicine, Jerusalem, Israel.
  • Rotshenker-Olshinka K; Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University School of Medicine, Jerusalem, Israel.
  • Grisaru-Granovsk S; Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University School of Medicine, Jerusalem, Israel.
Isr Med Assoc J ; 26(8): 486-492, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39254408
ABSTRACT

BACKGROUND:

Fetal weight estimation at term is a challenging clinical task.

OBJECTIVES:

To evaluate the association between peripheral white blood cell (WBC) count of the laboring women and neonatal birth weight (BW) for term uncomplicated pregnancies.

METHODS:

We conducted a single-center, retrospective cohort study (2006-2021) of women admitted in the first stage of labor or planned cesarean delivery. Complete blood counts were collected at admission. BW groups were categorized by weight (grams) < 2500 (group A), 2500-3499 (group B), 3500-4000 (group C), and > 4000 (group D). Two study periods were used to evaluate the association between WBC count and neonatal BW.

RESULTS:

There were a total of 98,632 deliveries. The dataset analyses showed a lower WBC count that was significantly and linearly associated with a higher BW; P for trend < 0.001 for women in labor. The most significant association was noted for the > 4000-gram newborns; adjusted odds ratio 0.97, 95% confidence interval 0.96-0.98; P < 0.001; adjusted for hemoglobin level, gestational age, and fetal sex. The 2018-2021 dataset analyses revealed WBC as an independent predictor of macrosomia with a significant incremental predictive value (P < 0.0001). The negative predictive value of the WBC count for macrosomia was significantly high, 93.85% for a threshold of WBC < 10.25 × 103/µl.

CONCLUSIONS:

WBC count should be considered to support the in-labor fetal weight estimation, especially valuable for the macrosomic fetus.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peso al Nacer / Macrosomía Fetal Límite: Adult / Female / Humans / Newborn / Pregnancy Idioma: En Revista: Isr Med Assoc J Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Israel
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peso al Nacer / Macrosomía Fetal Límite: Adult / Female / Humans / Newborn / Pregnancy Idioma: En Revista: Isr Med Assoc J Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Israel