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Exploring Gender Differences in the Association Between TyG Index and COPD: A Cross-Sectional Study from NHANES 1999-2018.
Guo, Jun; Yang, Jie; Wang, Jinghua; Liu, Wei; Kang, Yingjie; Li, Zhi; Hao, Chen; Qi, Shuai.
Afiliación
  • Guo J; General Surgery, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
  • Yang J; Cadre Ward, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
  • Wang J; Nephrology, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
  • Liu W; General Surgery, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
  • Kang Y; General Surgery, Hebei Yiling Hospital, Shijiazhuang, People's Republic of China.
  • Li Z; General Surgery, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
  • Hao C; General Surgery, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
  • Qi S; General Surgery, Bethune International Peace Hospital, Shijiazhuang, People's Republic of China.
Int J Chron Obstruct Pulmon Dis ; 19: 2001-2010, 2024.
Article en En | MEDLINE | ID: mdl-39253040
ABSTRACT

Purpose:

This study examined gender differences in the association of Triglyceride-Glucose (TyG) index with the prevalence of chronic obstructive pulmonary disease (COPD), particularly in a non-diabetic population.

Methods:

The study leveraged data from the National Health and Nutrition Examination Survey (NHANES), spanning from 1999 to 2018, with a cohort of 23,456 participants. Logistic regression and restricted cubic spline analyses were employed to explore the relationship between the TyG index and COPD prevalence.

Results:

Statistical analyses revealed a significant positive association between the TyG index and COPD prevalence among non-diabetic women after adjustment for all covariates (OR=1.50; 95% CI, 1.08-2.08), supported by a linear relationship (P for non-linearity=0.298). No equivalent significant association was found in non-diabetic men (OR=1.00; 95% CI, 0.67-1.48). Within the diabetic group, the TyG index did not show a significant association with COPD prevalence, regardless of gender.

Conclusion:

Our study reveals a significant positive correlation between the TyG index and COPD prevalence in the non-diabetic population, marked by notable gender differences.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Glucemia / Biomarcadores / Encuestas Nutricionales / Enfermedad Pulmonar Obstructiva Crónica Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Int J Chron Obstruct Pulmon Dis Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Glucemia / Biomarcadores / Encuestas Nutricionales / Enfermedad Pulmonar Obstructiva Crónica Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Int J Chron Obstruct Pulmon Dis Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda