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A case report of diet elimination guided by food specific IgG4 achieved clinical cure for eczematous external otitis with finger paronychia.
Du, Yuteng; Yang, Boyun; Yao, Wo; Zhu, Yongbin; Tang, Xuxia; Wang, Huiying.
Afiliación
  • Du Y; Department of Allergy and Clinical Immunology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
  • Yang B; Department of Emergency Medicine, Hangzhou Third People's Hospital, Hangzhou, China.
  • Yao W; Department of Allergy and Clinical Immunology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
  • Zhu Y; Department of Allergy and Clinical Immunology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
  • Tang X; Department of Otolaryngology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
  • Wang H; Department of Otolaryngology, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou, China.
Medicine (Baltimore) ; 103(36): e39605, 2024 Sep 06.
Article en En | MEDLINE | ID: mdl-39252262
ABSTRACT
RATIONALE Eczematous external otitis (EEO) is the most difficult-to-treat otitis externa, and characterized by the symptoms of inflammation with hypersensitivity of the external ear canal skin. It is acknowledged as a chronic skin inflammation primarily caused by dermatological and allergic reactions. Food allergens are also considered a cause to induce the inflammation. However, the role of food specific IgG4 in this disease is unclear yet. PATIENT CONCERNS A 54-year-old woman complained of recurrent itching of the external auditory meatus for 3 years and nails chapping of hands for 2 years. DIAGNOSES AND

INTERVENTIONS:

She was diagnosed with EEO and underwent the therapeutic strategy as food elimination of egg, milk and wheat, guided by the result of food specific IgG4 together with probiotics on the basis of previous symptom controlling therapy.

OUTCOMES:

After 17 months' treatment, she was finally free of all the symptoms and the serum IgG4 specific to all foods are under normal limit. LESSONS To the best of our knowledge, it is the first report revealing the clinical significance of food specific IgG4 in EEO, and the successful treatment with diet elimination guided by food specific IgG4 threw a new light on the clinical management of refractory EEO.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otitis Externa / Inmunoglobulina G / Hipersensibilidad a los Alimentos Límite: Female / Humans / Middle aged Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otitis Externa / Inmunoglobulina G / Hipersensibilidad a los Alimentos Límite: Female / Humans / Middle aged Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos